DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4360 and LOC102552527

DIOPT Version :9

Sequence 1:	NP_650879.1	Gene:	CG4360 / 42413	FlyBaseID:	FBgn0038787	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	XP_038956107.1	Gene:	LOC102552527 / 102552527	RGDID:	7689541	Length:	628	Species:	Rattus norvegicus

Alignment Length:	428	Identity:	137/428 - (32%)
Similarity:	188/428 - (43%)	Gaps:	106/428 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 KKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDKAFRQISTLTNHVKIHTGEKPFTCNICA 204
            |..:|::|...|.|.|||:.|.::||.|:||||:.|..:|..:|:|..|..:|.|.||:.|..|.
  Rat   205 KPYKCNLCDKSFSQSTTLKTHQRLHTGEKPYKCRECGMSFPYLSSLKVHQNLHPGAKPYKCKECD 269

  Fly   205 KDFRQQSTLINHIKTHKAAESSTPTSLLNYQPQTGSGKHRKSQMHQAYQQQHQRVQISKTLYSGS 269
            |.|..:||||.|.:.|                 ||.
  Rat   270 KSFTIKSTLIKHQRNH-----------------TGE----------------------------- 288

  Fly   270 YSSPAAEELVKPFQCSVCKRRFPQLSTLHNHERTHIDPKPYKCETCDKSFSQLATLANHKKIHTG 334
                      ||:.|:||.|.|.|.:.|..|:|.|...|||||:.|.|||:|.::|..|:.:|||
  Rat   289 ----------KPYTCNVCDRSFRQCANLKTHQRLHTGEKPYKCKECGKSFTQSSSLKKHQNLHTG 343

  Fly   335 DKPYTCSYCHMQFRQQSTLTNHLKTHTHQIAPGGVGGAGGGGGAVTATVDHSMPAPLAPGTQQLT 399
            .|||.|..|...|.::||||.|.:.||.: .|......|....:.|....|          |.|.
  Rat   344 KKPYKCEECDRSFTEKSTLTTHKRIHTGK-KPYKCNSCGKSFNSCTNLKTH----------QTLH 397

  Fly   400 SGLLP---NNLHGSTANIIQLDHHPLLH---------FLDGSTTVSSVVATAAANTKVEHFQAGG 452
            :|..|   .....|...:..|..|..||         ..|.|.|:.|.:.|    .::.|
  Rat   398 TGEKPYKCKECGKSFPYMSSLKIHQNLHPGEKPYTCKECDKSFTLKSSLRT----HQIIH----- 453

  Fly   453 SPSGRMTVVGTINMLKGDNPDRPFGCSVCQRFFSQQSTLVNHIKTHTGEKPYKCKICEVNFRQVA 517
                              ..::|:.|:||.:.|:|.:.|..|.:.||||||||||.|..:|...:
  Rat   454 ------------------TGEKPYKCNVCDKSFNQCTNLKTHQRLHTGEKPYKCKECGKSFHYWS 500

  Fly   518 TLNNHMKIHTGEKPYNCSFCPKQFRQKSTLQNHLRVHT 555
            :|.:|..:|||||||.|..|.|.|.:||||..|.|:||
  Rat   501 SLKSHQSLHTGEKPYKCKECDKSFTEKSTLIKHQRIHT 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4360	NP_650879.1	C2H2 Zn finger	144..164	CDD:275368	8/19 (42%)
		zf-H2C2_2	157..181	CDD:290200	11/23 (48%)
		C2H2 Zn finger	172..192	CDD:275368	6/19 (32%)
		zf-H2C2_2	185..209	CDD:290200	10/23 (43%)
		C2H2 Zn finger	200..220	CDD:275368	9/19 (47%)
		C2H2 Zn finger	284..304	CDD:275368	9/19 (47%)
		zf-C2H2_8	287..363	CDD:292531	36/75 (48%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		C2H2 Zn finger	340..360	CDD:275368	8/19 (42%)
		C2H2 Zn finger	478..498	CDD:275368	7/19 (37%)
		zf-H2C2_2	491..515	CDD:290200	14/23 (61%)
		C2H2 Zn finger	506..526	CDD:275368	6/19 (32%)
		zf-H2C2_2	519..543	CDD:290200	13/23 (57%)
		C2H2 Zn finger	534..554	CDD:275368	10/19 (53%)
LOC102552527	XP_038956107.1	KRAB	5..45	CDD:396083
		COG5048	165..594	CDD:227381	137/428 (32%)
		C2H2 Zn finger	181..201	CDD:275368
		C2H2 Zn finger	209..229	CDD:275368	8/19 (42%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	265..285	CDD:275368	9/19 (47%)
		C2H2 Zn finger	293..313	CDD:275368	9/19 (47%)
		C2H2 Zn finger	321..341	CDD:275368	8/19 (42%)
		C2H2 Zn finger	349..369	CDD:275368	8/19 (42%)
		C2H2 Zn finger	377..397	CDD:275368	4/29 (14%)
		C2H2 Zn finger	405..425	CDD:275368	3/19 (16%)
		C2H2 Zn finger	433..453	CDD:275368	5/23 (22%)
		C2H2 Zn finger	461..481	CDD:275368	7/19 (37%)
		C2H2 Zn finger	489..509	CDD:275368	6/19 (32%)
		C2H2 Zn finger	517..537	CDD:275368	10/19 (53%)
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	573..593	CDD:275368
		C2H2 Zn finger	606..626	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910