DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4360 and LOC101883356

DIOPT Version :9

Sequence 1:	NP_650879.1	Gene:	CG4360 / 42413	FlyBaseID:	FBgn0038787	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	XP_009290247.2	Gene:	LOC101883356 / 101883356	-ID:	-	Length:	777	Species:	Danio rerio

Alignment Length:	516	Identity:	143/516 - (27%)
Similarity:	211/516 - (40%)	Gaps:	157/516 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 GGSHTPISPMKQEVQSVISEEEVVVDDPRKKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHC 175
            |.|.:.:...||..::         .:.::..:|..|...|....:|:.|.:|||.|:|:||.:|
Zfish    61 GKSFSQLDSYKQHQKT---------HEDKRDHECLQCGKSFTTAGSLKIHQRIHTGEKPHKCSYC 116

  Fly   176 DKAFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPQTGS 240
            :|:|.....|.:|.:|||||||:.|..|.|.|:.:|:|..|:..|...:..|.|       |.|.
Zfish   117 EKSFSHSGHLKSHERIHTGEKPYHCTQCGKSFKDKSSLTYHLLVHTGEKPFTCT-------QCGH 174

  Fly   241 GKHRKSQMHQAYQQQHQRVQISKTLYSGSYSSPAAEELVKPFQCSVCKRRFPQLSTLHNHERTHI 305
            .....|.:     :||.|:..::                ||:.|..|::||.:|.....|::||.
Zfish   175 DFRSSSNL-----KQHMRIHTNE----------------KPYACLFCEKRFSRLCDCKRHQKTHT 218

  Fly   306 DPKPYKCETCDKSFSQLATLANHKKIHTGDKPYTCSYCHMQFRQQSTLTNHLKTHTHQIAPGGVG 370
            ..:.::|..|.|||:|..:|..|:.||||:||:.||||...|.:.|.|.:|.:.||.:
Zfish   219 GERDHECLQCGKSFTQSGSLKIHQMIHTGEKPHKCSYCEKSFSRSSHLKSHERIHTGE------- 276

  Fly   371 GAGGGGGAVTATVDHSMPAP-LAPGTQQLTSGLLPNNLHGSTANIIQLDHHPLLHFLDGSTTVSS 434
                              .| ..|..|:            |..:...|.:|.|:|  .|....||
Zfish   277 ------------------KPYCCPPCQK------------SFKDSCSLTYHLLVH--TGEKPFSS 309

  Fly   435 --VVATAAAN-----------------------------TKVEHF----QAGGS-------PSGR 457
              ::.|..|:                             ||..|.    |.|.|       ...|
Zfish   310 YPIIKTRRASKLSGDHSDQMEENEQRQEEDEERNFNTKGTKTTHLHSCRQCGKSFRRKSKLKKHR 374

  Fly   458 MTVVGTINMLKGDNPDRPFGCSVCQRFFSQQSTLVNHIKT------------------------- 497
            .|..|          ::|:.|:.|.:.|||..:...|.||
Zfish   375 KTHAG----------EKPYTCTECGKSFSQLDSYKQHQKTHEDKRDHECLQCGKSFTTAGHLKIH 429

  Fly   498 ---HTGEKPYKCKICEVNFRQVATLNNHMKIHTGEKPYNCSFCPKQFRQKSTLQNHLRVHT 555
               |||||||||..||.:|.|.:.|..|.:||||||||:|:.|.|.::.||:|..||.|||
Zfish   430 QRIHTGEKPYKCSYCEKSFSQSSDLKKHERIHTGEKPYHCTQCGKSYKDKSSLTYHLLVHT 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4360	NP_650879.1	C2H2 Zn finger	144..164	CDD:275368	5/19 (26%)
		zf-H2C2_2	157..181	CDD:290200	12/23 (52%)
		C2H2 Zn finger	172..192	CDD:275368	6/19 (32%)
		zf-H2C2_2	185..209	CDD:290200	13/23 (57%)
		C2H2 Zn finger	200..220	CDD:275368	7/19 (37%)
		C2H2 Zn finger	284..304	CDD:275368	6/19 (32%)
		zf-C2H2_8	287..363	CDD:292531	31/75 (41%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		C2H2 Zn finger	340..360	CDD:275368	8/19 (42%)
		C2H2 Zn finger	478..498	CDD:275368	8/47 (17%)
		zf-H2C2_2	491..515	CDD:290200	15/51 (29%)
		C2H2 Zn finger	506..526	CDD:275368	7/19 (37%)
		zf-H2C2_2	519..543	CDD:290200	13/23 (57%)
		C2H2 Zn finger	534..554	CDD:275368	8/19 (42%)
LOC101883356	XP_009290247.2	COG5048	26..420	CDD:227381	109/444 (25%)
		C2H2 Zn finger	29..49	CDD:275368
		C2H2 Zn finger	57..77	CDD:275368	4/24 (17%)
		C2H2 Zn finger	85..105	CDD:275368	5/19 (26%)
		C2H2 Zn finger	113..133	CDD:275368	6/19 (32%)
		C2H2 Zn finger	141..161	CDD:275368	7/19 (37%)
		C2H2 Zn finger	169..189	CDD:275368	7/31 (23%)
		C2H2 Zn finger	197..217	CDD:275368	6/19 (32%)
		C2H2 Zn finger	225..245	CDD:275368	8/19 (42%)
		C2H2 Zn finger	253..273	CDD:275368	8/19 (42%)
		C2H2 Zn finger	281..301	CDD:275368	6/31 (19%)
		COG5048	354..737	CDD:227381	49/147 (33%)
		C2H2 Zn finger	357..377	CDD:275368	4/19 (21%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		C2H2 Zn finger	413..433	CDD:275368	0/19 (0%)
		C2H2 Zn finger	441..461	CDD:275368	7/19 (37%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..517	CDD:275368
		C2H2 Zn finger	525..545	CDD:275368
		C2H2 Zn finger	553..573	CDD:275368
		C2H2 Zn finger	581..601	CDD:275368
		C2H2 Zn finger	609..629	CDD:275368
		C2H2 Zn finger	637..657	CDD:275368
		C2H2 Zn finger	665..685	CDD:275368
		C2H2 Zn finger	693..713	CDD:275368
		C2H2 Zn finger	721..741	CDD:275368
		C2H2 Zn finger	749..769	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24377
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100