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Protein Alignment CG42668 and Osbpl8

DIOPT Version :9

Sequence 1:	NP_001189250.2	Gene:	CG42668 / 42412	FlyBaseID:	FBgn0261550	Length:	990	Species:	Drosophila melanogaster
Sequence 2:	NP_780698.2	Gene:	Osbpl8 / 237542	MGIID:	2443807	Length:	889	Species:	Mus musculus

Alignment Length:	925	Identity:	416/925 - (44%)
Similarity:	572/925 - (61%)	Gaps:	96/925 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 MGASNQSLGVSVGAASSVSGISITPPNSAGL--RQSTVFDFKFKRRPSLKVLMTKLPST------ 167
            :|.|...||.|...|:|.....:||...:..  |.:.....:...:|||.      |::
Mouse    16 LGDSKDVLGPSTVVANSDEPQHLTPGKMSQRQGRDANPTPTRDLPQPSLS------PASLHSQGF 74

  Fly   168 ----DSLSNSPAPSSPGIANWASDNRDGNVADKSAADAAKLNRKESYKAQRKNYRREKKRVASEL 228
                :.:|.:...||..::...|:::..|.::|.::.::||.:|||.|.|:||||.||||...||
Mouse    75 ERGKEDISQNKDDSSLSMSKSKSESKLYNGSEKDSSTSSKLTKKESLKVQKKNYREEKKRATKEL 139

  Fly   229 MNSLQDPAVIVLADWLKVRGTLKSWTKLWCVLKPGLLLIYKSQKTKSSHWVGTVMLTSCQVIERP 293
            ::::.||:|||:|||||:|||||||||||||||||:|||||:|  |:..|||||:|.:|::||||
Mouse   140 LSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQ--KNGQWVGTVLLNACEIIERP 202

  Fly   294 SKKDGFCFKLFHPLEQSIWAPRGPDKETIGAVVQPLPTAYLIFRAPSQAAGKCWMDALELSLRCS 358
            ||||||||||||||||||||.:||..|.:|::.||||::|||.||.|::.|:||||||||:|:||
Mouse   203 SKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCS 267

  Fly   359 ALLLR-------------SNSSTGTAPTSSYIGEPLPVSHETQWSEADYEK-HFNDHDLDAD--- 406
            :||.|             |:.||............|......|.::::.|: ||.|.||.:|
Mouse   268 SLLKRTMVREGKEHDLSISSDSTHVTLYGLLRANNLHSGDNFQLNDSEIERQHFKDQDLYSDKSD 332

  Fly   407 -----SQNEAPNAVMSGLESESESDPAEPAQDDVVDQQCV----ETSYVPFTEEEFGEQGE--QV 460
                 ..:|:.|.|: |...||::|.:|...|..:|.:.|    ||:|:..:.||.||.||  |.
Mouse   333 KENDPEHDESDNEVL-GKSEESDTDTSERQDDSYIDPEPVEPLKETTYMEQSHEELGEAGEASQT 396

  Fly   461 EELAEENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTR 525
            |.::||||||||.::||||||||||:|||||||||||||||||||.|||||.||:|..|::.:.|
Mouse   397 ETVSEENKSLIWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFR 461

  Fly   526 MKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHP-SGSRTFYIAEQVSHHPPVSAFYVTNR 589
            :|.||:||||.||||||||||||||||||.|||.|.|| :.|:|||||||||||||:|||||:||
Mouse   462 LKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNR 526

  Fly   590 EDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRGECYTATTPYAHCKGILMGTLSMELGGKI 654
            :|||.::.||||||||||||.||:|||.|.:|.|.|||.|..|.|||||||||.||:::||||.:
Mouse   527 KDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTV 591

  Fly   655 NIECENTGYRTELEFKLKPFLGGADATNVVVGKIKLGKETLATINGHWDKECRVKDSKTGEETVL 719
            ||.|:.|||...||||||||||.:|..|.:.||:|||||.|||:.||||.|..:.|.||....:.
Mouse   592 NITCQKTGYSAILEFKLKPFLGSSDYVNQISGKLKLGKEVLATLEGHWDSEVFINDKKTDNSEIF 656

  Fly   720 FKVDAETRSKRLTRYMVPLDLQEANESQRLWQRVSEAIANEDQVAATEEKTVLEERQRADAKERL 784
            :....:.:..||.|:.|..:.|:..||::|||||::||..:||..||:||.||||.||..|::|.
Mouse   657 WNPTPDIKQWRLIRHTVKFEEQDDFESEKLWQRVTKAINAKDQTEATQEKYVLEEAQRQAARDRK 721

  Fly   785 SSDSVHMPDLFELDSY-GQWLYKYADLRPWDSRNDVRQYECQFKVLTQTRHKSVPIVHGAEMIH- 847
            :.....:..|||||.. |:|.||::|.||||..||:.|:|....:.|:.:|:: |:|...:|.|
Mouse   722 TKTQEWVCKLFELDPLTGEWHYKFSDTRPWDPLNDMIQFEKDGVIQTKVKHRT-PMVSVPKMKHK 785

  Fly   848 PLRSSIETLSRTQRQSPAGQPLPPGGSAVPKAKNKSLVLAPRDTNSDSSQSPQGAVKRSSSSAIK 912
            |        :|.|::...|...|.     |..         :|::...:||.:.:.:|.....:.
Mouse   786 P--------TRQQKKVVKGYSSPE-----PDI---------QDSSGSEAQSVKPSTRRKKGIDLG 828

  Fly   913 QLALAVDQVNRVLEQHTRQLNEISQRLERMQYSPPPSSMSAHSLHMLGGGVSQSTVIKSLIYALI 977
            .:..:::.:.:..|:..|.:..:..                   |:|....:....::...|.:|
Mouse   829 DIQSSIESIKQTQEEIKRNIMALRN-------------------HLLSSTPATDYFLQQKDYFVI 874

  Fly   978 GLAFSL--ILRWLFK 990
            .|...|  |:.::||
Mouse   875 FLLILLQVIINFIFK 889

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.