Protein Alignment CG42668 and osbpl8

DIOPT Version :9

• Sequence 1: NP_001189250.2
• Gene: CG42668 / 42412
• FlyBaseID: FBgn0261550
• Length: 990
• Species: Drosophila melanogaster
• Sequence 2: XP_012814032.1
• Gene: osbpl8 / 100145444
• XenbaseID: XB-GENE-5961068
• Length: 988
• Species: Xenopus tropicalis
• Alignment Length: 1048
• Identity: 456/1048 - (43%)
• Similarity: 600/1048 - (57%)
• Gaps: 169/1048 - (16%)

  Fly    28 SAPAVASSTPIRINSAKQQGAAGGGDTLA----------HPATPHSHSMPGTPHQQPQSSSVPTG 82
            |:..||:|....|..||.....|....|:          .|...|||:.    |.:    :|...
 Frog    25 SSHLVANSESPLILPAKMSQRQGKDAYLSPTKDLVQATLSPGIIHSHAF----HLR----TVTLN 81

  Fly    83 GHL-LQLQAPL---PSAGGGTGAGAVTPSGLSMGASNQSLGVSVGAASSVSGISITPPNSAGLRQ 143
            .|| ::.:.||   ..||...|.....|.|..: ..|.|.|          |.:...|...|
 Frog    82 KHLAMKEEGPLRRRSCAGVSPGTFLPRPDGRKL-VRNASFG----------GYNELSPALPG--- 132

  Fly   144 STVFDFKFKRRPSLKVLMTKLPSTDSLSNSPAPSSPGIANWASDNRDGNVADKSAADA-AKLNRK 207
               ||     :...:||.:|..::.|:|.|           .|:::..|.:::..|.| :||.:|
 Frog   133 ---FD-----KGKDEVLQSKEDTSISMSKS-----------KSESKLYNGSERDIASASSKLTKK 178

  Fly   208 ESYKAQRKNYRREKKRVASELMNSLQDPAVIVLADWLKVRGTLKSWTKLWCVLKPGLLLIYKSQK 272
            ||.|.|:||||.||||...||::::.||:|||:|||||:|||||||||||||||||:|||||:
 Frog   179 ESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKT-- 241

  Fly   273 TKSSHWVGTVMLTSCQVIERPSKKDGFCFKLFHPLEQSIWAPRGPDKETIGAVVQPLPTAYLIFR 337
            .|:..|||||:|.:|::||||||||||||||||||||||||.:||..|.:|::.||||::|||.|
 Frog   242 PKNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIR 306

  Fly   338 APSQAAGKCWMDALELSLRCSALLLRSNSSTG------TAPTSSYIG-------EPLPVSHETQW 389
            |.|::.|:||||||||:|:||:||.|:....|      ::..:|::|       ..|..:...|.
 Frog   307 AASESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSADNSHVGFYGLLRVNNLHSNENFQL 371

  Fly   390 SEADYEKHF--------------NDHDLDADSQNEAPNAVMSGLESESESDPAEPAQDDVVD--- 437
            ::::.|:|.              ||||.| :|.|:.     .|...||:||.:|...|..||
 Frog   372 NDSEIERHHFKDQDTYSDKSDKDNDHDHD-ESDNDG-----LGKSEESDSDTSERQDDSFVDPDP 430

  Fly   438 -QQCVETSYVPFTEEEFGEQGE--QVEELAEENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSF 499
             :...||:||....||.||.||  |.|.::||:|||||.::||||||||||||||||||||||||
 Frog   431 PELIKETTYVEEAHEELGEAGEASQTETVSEEHKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSF 495

  Fly   500 LDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHP- 563
            ||||||.|||||.||:|..|::.::|||.||:||||.||||||||||||||||||.|||.|.||
 Frog   496 LDKLSDYYYHADFLSEAALEENPYSRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPR 560

  Fly   564 SGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRGEC 628
            :.|:||||:||||||||||||||:||:|||.::.||||||||||||.||:|||...:|.|.|||.
 Frog   561 TSSKTFYISEQVSHHPPVSAFYVSNRKDGFCLSGSILAKSKFYGNSLSALLEGEGRLTFLNRGED 625

  Fly   629 YTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLGGADATNVVVGKIKLGKE 693
            |..|.|||||||||.||:::||||.:.|.||.|.|...|:||||||||..|:.|.:.||||||||
 Frog   626 YLMTMPYAHCKGILYGTMTLELGGSVTITCEKTSYSATLDFKLKPFLGSDDSVNQISGKIKLGKE 690

  Fly   694 TLATINGHWDKECRVKDSKTGEETVLFKVDAETRSKRLTRYMVPLDLQEANESQRLWQRVSEAIA 758
            .|||:.||||.|..:.|.||......:....|.|..||.|..|..:.|...||:|||:.|:.||.
 Frog   691 VLATLEGHWDSEVFIHDKKTDVFETFWNPTLEIRHHRLIRCTVNQEEQGEFESERLWRLVTLAIN 755

  Fly   759 NEDQVAATEEKTVLEERQRADAKERLSSDSVHMPDLFELDSY-GQWLYKYADLRPWDSRNDVRQY 822
            |:||..||:||.||||.||..||||.:........|||.|.. |:|.|||||.||||..||:.|:
 Frog   756 NKDQTEATQEKFVLEEAQRKAAKERKAKGEEWTCKLFEQDPLTGEWHYKYADTRPWDPLNDLIQF 820

  Fly   823 ECQFKVLTQTRHKSVPIVHGAEMIHPLRSSIETLSR--TQRQSPAGQPLPPGGSAVPKAKNK--- 882
            |....:.|:.||:: |:|....:|:        ||.  .:|:..:.|      ..|||.|:|
 Frog   821 ENDGVIQTKVRHRT-PMVRSGSVIN--------LSNQGAKREKCSYQ------VCVPKLKHKASG 870

  Fly   883 ------SLVLAPRDTNSDSSQSPQGAVKRSSSSAIKQLA--------------------LAVDQV 921
                  |...:|...|.|||.|..||......:.:|.||                    .|:|.:
 Frog   871 QQKKGESGCSSPELDNQDSSGSEAGASDEEQMNVLKPLAHLLSHNNRVRKKGADHGELQSAIDSI 935

  Fly   922 NRVLEQHTRQLNEISQRLERMQYSPPPSSMSAHSLHMLGGGVSQSTVIKS----LIYALIGLAFS 982
            .:..|:..|.:..:..|:          |::..|        ::::.::.    :|:.||.|  .
 Frog   936 KKTQEEINRNIIALRNRV----------SVNTSS--------TENSFLQQRDYFIIFFLITL--Q 980

  Fly   983 LILRWLFK 990
            :.:.:|||
 Frog   981 IAVSYLFK 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42668	NP_001189250.2	PH_OPR5_ORP8	231..361	CDD:270103	90/129 (70%)
		PH	238..356	CDD:278594	84/117 (72%)
		Oxysterol_BP	471..796	CDD:279564	205/325 (63%)
		Prefoldin	<849..943	CDD:238453	26/124 (21%)
osbpl8	XP_012814032.1	PH_OPR5_ORP8	202..331	CDD:270103	91/130 (70%)
		PH	209..325	CDD:278594	84/117 (72%)
		Oxysterol_BP	467..805	CDD:279564	211/337 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	406	1.000	Domainoid score	I700
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68813
Inparanoid	1	1.050	737	1.000	Inparanoid score	I605
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D127430at33208
OrthoFinder	1	1.000	-	-		FOG0002062
OrthoInspector	1	1.000	-	-		oto104590
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1035
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060