Protein Alignment Nlg4 and Ces2f

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001073334.2
• Gene: Ces2f / 71903
• MGIID: 1919153
• Length: 561
• Species: Mus musculus
• Alignment Length: 707
• Identity: 186/707 - (26%)
• Similarity: 285/707 - (40%)
• Gaps: 192/707 - (27%)

  Fly    18 VLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQ 82
            :|:..:|..|..:::       ...|..|..|::.|..:.|...:  .....|||:|:|.||...
Mouse    17 LLVLLLHVKGLDSSE-------ASPIRNTHTGQVRGKFVHLTDIK--AGAHNFLGIPFAKPPVGP 72

  Fly    83 NRFSPTRAPAPWDGIRISDKYSPVCPQR--LPNIQNETAALEKMPKGRLEYLKRLLPFLENQSED 145
            .||:|..||.||.|:|.......:|.|.  :.|::.            |:.:|.:||.. :.|||
Mouse    73 LRFAPPEAPEPWSGVRDGTSQPAMCLQNDDIVNLEG------------LKIIKMILPPF-SMSED 124

  Fly   146 CLYLNVFSPVNA--GANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGF 208
            |||||:::|.:|  |:|   |||:|::||........:.|||||||:..:||||...|||||.||
Mouse   125 CLYLNIYTPAHAQEGSN---LPVMVWLHGGGLVAGMASMYDGSVLAATEDVVVVVTQYRLGIPGF 186

  Fly   209 LNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVR 273
            .:....   .|| .|:|.:||.|||||:||||..|||:|:||||.|...|...:::.:.|| :.:
Mouse   187 YSTGDE---QAR-GNWGFLDQTAALHWVQQNIANFGGNPDSVTLFGQSAGGTSVSFHVLSP-VSQ 246

  Fly   274 GLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLAD 338
            |||||||:.||.|.....:.:.|.:...|:|....|.     ..:.|.:|.|||...     .|:
Mouse   247 GLFHRAIMESGVALLPTIIPDSPEMIFTKVANLSGCE-----TSNSEALVRCLRGKS-----EAE 301

  Fly   339 IQAPNFLTSFGPS-VDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGG 402
            |.|.:....|.|: |||             ..:.|:.::..|.:.|.....
Mouse   302 ILAMSKAFRFMPAVVDG-------------KFLPRHPKKLLASADFHPVPS-------------- 339

  Fly   403 GGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGE------SIWRFSAHDIQNGFEGERRDKII 461
                                        :.||...|      .|::||              :.|
Mouse   340 ----------------------------IIGVNNDEYGWIIPKIFKFS--------------QTI 362

  Fly   462 RTYVRNAYNYHL----------NEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVR 516
            |...||.....:          :|....::.||.   |.::.|...:......:.|...:.|.::
Mouse   363 RKINRNNLKAIMKITTEQMMLPSECGDLLIEEYL---RDTEDPWTLQMQFREMIGDFLIIIPALQ 424

  Fly   517 AGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDY--PQRMGTVH 579
            ......:::|                              .|||.|.:::....|  |..:...|
Mouse   425 VARFQRSHAP------------------------------VYFYEFQHRSSLLKYFRPWHVKADH 459

  Fly   580 GEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNR 644
            |::|..|||:    .|.....::|..|..||..:|.:|.||||.||||     ...||.
Mouse   460 GDELYLIFGS----FFWGLKFSFTAEEKLLSRKMMKYWANFARYGNPN-----SEDLPY------ 509

  Fly   645 FRSITW--ENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIPE--LHRAGMEDVI 697
                 |  .|.|.|   ||::.:.|.:.:..:|.:|..|.:.:|:  |...|..|.|
Mouse   510 -----WPASNQDDL---YLQLDIHPSVGHALKARRLPFWTKTLPQKMLELKGNHDKI 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	177/662 (27%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	177/665 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810