Protein Alignment Nlg4 and Ces2j

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_038953911.1
• Gene: Ces2j / 685645
• RGDID: 1591368
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 661
• Identity: 183/661 - (27%)
• Similarity: 264/661 - (39%)
• Gaps: 168/661 - (25%)

  Fly    43 IVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVC 107
            |..|..|::.|..:.:...:  ..:..|||:|:|.||....||:|...|.||.|:|.:.....:|
  Rat    53 IRNTHTGQVRGSFVHVKDTK--SGIHTFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMC 115

  Fly   108 PQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHG 172
                  :|.....||.|.:..|..|.        .||||||||::.|.:| ..:..|||:|:|||
  Rat   116 ------LQTAMMNLEGMKETELTKLP--------MSEDCLYLNIYVPAHA-HEDSNLPVMVWIHG 165

  Fly   173 ESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQ 237
            ......|.:..|.|.||:..|:|:|::.||||:|||.:....   ||| .|:|.:||||||.|:|
  Rat   166 GGLVGGSASMNDASTLAATEEIVIVSIQYRLGVLGFFSTGDQ---HAR-GNWGYLDQMAALRWVQ 226

  Fly   238 QNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIK 302
            |||..|||:.:|||:.|...|...::..:.|| |.:|||||||:.||.|... .|:.|......|
  Rat   227 QNIAYFGGNRDSVTIFGVSAGGTSVSSHVVSP-MSKGLFHRAIMQSGVALLP-GLISDTSEVVYK 289

  Fly   303 -LAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPS-VDGVVIRPGHSNLD 365
             :|....|...|.     |.::.|||....:     :|.|.|.:....|. |||..: |.|.
  Rat   290 TVANLSGCEASDS-----EALIRCLRAKSKQ-----EILAINQVFKMIPGVVDGKFL-PKHP--- 340

  Fly   366 IDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDV 430
             .:|:|      |.|.....|
  Rat   341 -QELLA------SKDFHPVPS-------------------------------------------- 354

  Fly   431 LFGVVTGESIWR----FSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTS 491
            :.||.|.|..|.    ...:.|.|....|.....::  :..|......|....|:.||..
  Rat   355 IIGVNTDECGWGVPTILGLYHIINNITRETLPAALK--IAAAQMMLPPECIDLIMEEYMG----- 412

  Fly   492 QHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGR 556
                   ||..|....|||...:   ||.:.......|:....:.:|
  Rat   413 -------DTEDAETLQAQFKEML---GDFIFVIPALQVAHFQRSQAP------------------ 449

  Fly   557 CYFYVFDY------QTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHF---PQNYTKSETALSEA 612
            .|||.|.:      |.:. .||:   ..||:|..::||       |:|   ..:.|:.|..|...
  Rat   450 VYFYEFQHLLSFIKQVRP-FYPK---ADHGDDTVFVFG-------SYFWGMTFDLTEEEELLKRR 503

  Fly   613 VMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLH-QKYLEIGMKPRIKNHFRAH 676
            ||.:|.|||||||||     ...||           .|...|  | ::||::..:|.:....:|.
  Rat   504 VMKYWANFARTGNPN-----GEDLP-----------HWPVLD--HDEQYLQLNSQPAVGRALKAR 550

  Fly   677 QLSIWLRLIPE 687
            :|..|.:.:|:
  Rat   551 RLQFWTKTLPQ 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	181/653 (28%)
Ces2j	XP_038953911.1	COesterase	50..555	CDD:395084	181/653 (28%)