Protein Alignment Nlg4 and nlgn3b

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_005165239.1
• Gene: nlgn3b / 567415
• ZFINID: ZDB-GENE-060526-197
• Length: 846
• Species: Danio rerio
• Alignment Length: 871
• Identity: 280/871 - (32%)
• Similarity: 400/871 - (45%)
• Gaps: 216/871 - (24%)

  Fly    44 VQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCP 108
            |.|..|||.|:.:.: :...|..|:.:||||||.||..:.||.|..||:.|.|:|.:.::.||||
Zfish    48 VNTALGRLRGMRVAV-ATEGLGPVDQYLGVPYAAPPVGEKRFMPPDAPSAWSGVRNATRFPPVCP 111

  Fly   109 QRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAG--------------- 158
            |.:.|...:.    .||......:..:..:|:.|||||||:|::.|..:|
Zfish   112 QTVRNAVPDI----MMPVWATYNMDTVATYLQEQSEDCLYMNIYVPTQSGTKRTGDMSADTERTE 172

  Fly   159 ------ANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHA 217
                  :.:...||::||||.|:...:||..|||||||||.|:|:|||||:||||||:...
Zfish   173 DDGLRDSRDDPRPVMLFIHGGSYMEGTGNIMDGSVLASYGNVIVITLNYRVGILGFLSTGD---- 233

  Fly   218 HARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILM 282
            .|...||||:||:.||.||.:||..|||||..||:.|.|.||:|:: |:|......|||||||:.
Zfish   234 QAAKGNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVS-LLTLSHHSEGLFHRAIIQ 297

  Fly   283 SGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTS 347
            ||||.|||::...||.:...||:.|.|.:.|.     :.:|.|::.....:|...:||...|..:
Zfish   298 SGSALSSWSVNYQPVKYTRLLAERVGCNVLDT-----QDLVLCMQKRSYRELVEQEIQPARFHVA 357

  Fly   348 FGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGG 412
            |||.:||.:|..     |.:.||.:                                       |
Zfish   358 FGPVIDGDLIPD-----DPEVLMEQ---------------------------------------G 378

  Fly   413 YFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDI---QNGFEGERRDKIIRTYVRNAYNY--- 471
            .|       :|    ||::.||..||. :||....:   :.|..|...|..:..:|.:.|.|
Zfish   379 EF-------LN----YDIMLGVNQGEG-FRFVEGVVEPEEGGVSGSDFDFTVSDFVDSLYGYPEG 431

  Fly   472 --HLNEIFYTIVNEYTDW-DRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSS 533
              .|.|   ||...|||| ||  .:|...|.|.||..:|.|:|.|.|...|:.|
Zfish   432 KDTLRE---TIKFMYTDWADR--DNPETRRKTLVAMFTDHQWVEPAVVTADLHA----------- 480

  Fly   534 TAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHF 598
            ..|||                  .:||.|.:..:....|....:.||::|||:||.||:.....|
Zfish   481 RYGSP------------------TFFYAFYHHCQSPMKPPWADSAHGDELPYVFGVPLIGPTELF 527

  Fly   599 PQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEI 663
            |.|:::::..||..||.:|||||:||:||:...||:.. :..:.|||..:||..|.|..|.||.|
Zfish   528 PCNFSRNDIMLSAVVMTYWTNFAKTGDPNKPVPQDTKF-IHTKANRFEEVTWAKYGPHDQLYLHI 591

  Fly   664 GMKPRIKNHFRAHQLSIWLRLIPELHRAGMEDVIARHNLFRNHDDMDLYEGPVKPDPFGISTAAG 728
            |:|||:::|:||.:::.|..|:|.|:               |..||..|.......|..::|
Zfish   592 GLKPRVRDHYRATKVAFWKHLVPHLY---------------NLHDMFHYTSTTTRVPPLLTT--- 638

  Fly   729 ASGSSSSSSSSSRLLLVDEQLMMKKGRGLNGSAYLNGILGVTTVEPNNMYTTCIPIGGNYSSSGG 793
                .||.|::.|                                         | |||.:.:.|
Zfish   639 ----HSSHSATPR-----------------------------------------P-GGNKARTSG 657

  Fly   794 VFAPTTLANASSDTLASGFEAAGYAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLEVKT 858
            ...|.:.|.:....:|:..:      |||.||||||:|.|||.||||.||.:||::||     ::
Zfish   658 KQPPQSTARSGPLVIANPRD------YSTELSVTIAVGASLLFLNVLAFAALYYRKDK-----RS 711

  Fly   859 LQKQYQQRSLHQQVP-----YPPEPI 879
            .|....|.:..:|.|     |.|..|
Zfish   712 RQDTPPQPAPQRQTPPIDLNYAPTSI 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	228/666 (34%)
nlgn3b	XP_005165239.1	COesterase	40..609	CDD:278561	228/666 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	439	1.000	Inparanoid score	I1641
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	1	1.000	-	-		FOG0000662
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101617
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X375
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.830