Protein Alignment Nlg4 and cel.2

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001020344.2
• Gene: cel.2 / 565117
• ZFINID: ZDB-GENE-061110-10
• Length: 551
• Species: Danio rerio
• Alignment Length: 695
• Identity: 185/695 - (26%)
• Similarity: 278/695 - (40%)
• Gaps: 222/695 - (31%)

  Fly    35 KGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAP---WDG 96
            :||.||  .|.|..|.:.|   ...|...||.::||.|:|:|.||.:..:      |.|   |:|
Zfish    19 QGASLG--AVLTEGGMVQG---KSHSVGLLRYMDVFKGIPFAAPPGRLQK------PVPHPGWEG 72

  Fly    97 IRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANE 161
            :..:.:||..|.| |..:|.:|..                      ||||||||::.|.....:
Zfish    73 VLKATEYSKRCIQ-LNLLQTDTMG----------------------SEDCLYLNIWVPQGKTVS- 113

  Fly   162 KKLPVIVFIHGESFEWSSGNP--------YDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAH 218
            ..|||:|||:|..|....|..        |||..:|..|.|:|||.|||:|.:|||:..   .|.
Zfish   114 YNLPVMVFIYGGGFLLGGGQGANFLDNYLYDGEEIADRGNVIVVTFNYRVGSMGFLSTG---DAD 175

  Fly   219 ARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMS 283
            | ..||||.||.||:.|:.:||:.|||:|:::|:.|...|:..:|:.:.||.. :||..|||..|
Zfish   176 A-PGNYGLWDQHAAISWVHRNIKAFGGNPDNITIFGESAGSTSVNFQIISPKN-KGLIRRAISQS 238

  Fly   284 GSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLR--------------------D 328
            |.|...||:..:|..||.::||:|.|  |.|     ..:|.|||                    :
Zfish   239 GVALCPWAINRNPRKFAEEIAKKVGC--PTD-----SGMVACLRRTDPKAVTLAGKVRLATSATE 296

  Fly   329 VPLEDLYLADIQAPNFL-----TSFGPSVD-----GVVIRPGH--SNLDIDDLMARNSRRSSADS 381
            ..:.:|||:.:...:|:     |.||.:.|     ||....||  :.|||..:  .|:..::.:.
Zfish   297 PIVHNLYLSPVIDGDFIPDEPDTLFGNAADIDYIAGVNDMDGHIFATLDIPSI--NNALATTTEE 359

  Fly   382 GFQSSAGG-GGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSA 445
            ..|:.|.. ...:|..||                                         |..|..
Zfish   360 EVQALATALSKDRGQDAG-----------------------------------------IATFQE 383

  Fly   446 HDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQF 510
            :.:..|.:..:.|                 |..|:|...||:                     .|
Zfish   384 YTVNWGSKPNKED-----------------IKKTVVEMETDY---------------------IF 410

  Fly   511 VAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRM 575
            :.|...|..:.:.|:                           .|.|.|.|:|...::...:|..|
Zfish   411 LVPTQTALYLHSDNA---------------------------KSARTYSYLFSESSRIPIFPLWM 448

  Fly   576 GTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSK 640
            |..|.::|.|:||.|......:||::     ..:|:.::.:|||||:|||||   ..:|.:||
Zfish   449 GADHADELQYVFGKPFTTPLGYFPRH-----RDVSKYMIAYWTNFAQTGNPN---TGESKVPV-- 503

  Fly   641 ERNRFRSITWENY-DPLHQKYLEIGMK---PRIKNHFRAHQLSIW 681
                    ||..: :|.|| ||:|..|   ..:|...|...:..|
Zfish   504 --------TWPEFSNPGHQ-YLDINNKINTNSVKKMLRTRLVYYW 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	180/685 (26%)
cel.2	NP_001020344.2	COesterase	26..539	CDD:306613	180/684 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910