Protein Alignment Nlg4 and Cesl1

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_038953870.1
• Gene: Cesl1 / 501232
• RGDID: 1565666
• Length: 596
• Species: Rattus norvegicus
• Alignment Length: 708
• Identity: 201/708 - (28%)
• Similarity: 292/708 - (41%)
• Gaps: 177/708 - (25%)

  Fly     8 LLLRLLLLPTVLISWMHCAGAST---ADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEV 69
            :.||.|.|.: |.:.:.|...|:   .|..||..||      :|..|.|:         .:||.|
  Rat    36 MCLRSLFLVS-LATCVVCGNPSSPPVVDTMKGKVLG------KYASLEGV---------TQSVAV 84

  Fly    70 FLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAAL-EKMPKGRLEYLK 133
            |||||:|.||....||:|.:...||..::.:..|.|:|.|.....|.....| .:..|..|::
  Rat    85 FLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCSQDATKGQRMNDLLTNRKEKVHLQF-- 147

  Fly   134 RLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVT 198
                     ||||||||:::|.:. ..:.::||:|:|||........:.|||.||::|..||||.
  Rat   148 ---------SEDCLYLNIYTPADF-TKDSRMPVMVWIHGGGLTQGGASTYDGQVLSAYENVVVVA 202

  Fly   199 LNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACIN 263
            :.|||||.||.:....   |:| .|:|.:||:|||||:|.||..|||||.|||:.|...|...::
  Rat   203 IQYRLGIWGFFSTGDE---HSR-GNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVS 263

  Fly   264 YLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNC-TIPDDINRHHEQIVDCLR 327
            .|:.|| :.:.|:||||..||....:....:|....|.::|....| |....|      ||.|||
  Rat   264 VLVLSP-LSKNLYHRAISESGVVLITELFTKDVRPAAKQIADMAGCKTTTSAI------IVHCLR 321

  Fly   328 DVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLD--IDD-LMARNSRRSSADSGFQSSAGG 389
            ....|:  |.:|.....|.......|   .:..:..|.  ||| ::.::.:...|:..|.:
  Rat   322 QKTEEE--LLEIMEKMNLIKLSSQRD---TKESYHFLSTVIDDVVLPKDPKEILAEKNFNT---- 377

  Fly   390 GGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIW------RFSAHDI 448
                                                  ...:.|:...|..|      ||...|:
  Rat   378 --------------------------------------VPYIVGINKQECGWLLPTMMRFVPPDV 404

  Fly   449 QNGFEGERRDK--IIRTYVRNAYNYHLNE-IFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQF 510
                   :.||  .|....:.|..|.:.| |....:.:|.   :.|..||..||..:|.:.||.|
  Rat   405 -------KLDKKMAIMLLEKFASIYGIPEDIIPVAIEKYR---KGSDDPIKIRDGILAFIGDALF 459

  Fly   511 VAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDG-DYPQR 574
            ..|.|...           .....||:|                    .||::||.... ..|||
  Rat   460 CIPSVMVS-----------RDHRDAGAP--------------------TYVYEYQYYPSFSSPQR 493

  Fly   575 MGTV---HGEDLPYIFGAPLV-DGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSS 635
            ...|   |.:|:..:||||:: ||.|       :.|..||:.||.||.||||.||||     ...
  Rat   494 PKDVVGDHADDVYSVFGAPILRDGAS-------EEEIKLSKMVMKFWANFARNGNPN-----GRG 546

  Fly   636 LPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLI----PELH 689
            ||           .|..||. .::||:||...:.....:|.:::.|.:|:    |:.|
  Rat   547 LP-----------HWPQYDQ-KEEYLQIGATTQQSQGLKAEEVAFWTQLLAKRQPQPH 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	185/656 (28%)
Cesl1	XP_038953870.1	COesterase	57..580	CDD:395084	190/672 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000