Protein Alignment Nlg4 and Ces2h

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001037723.1
• Gene: Ces2h / 498940
• RGDID: 1560889
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 672
• Identity: 189/672 - (28%)
• Similarity: 288/672 - (42%)
• Gaps: 168/672 - (25%)

  Fly    46 TRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQR 110
            |..|::.|.::.:.....  .|..|||:|:|.||....||:|..||.||.|:|....:..:|
  Rat    35 THTGQILGSLIHMKGLDV--GVHSFLGIPFAKPPIGPLRFAPPEAPEPWSGVRDGTSHPAMC--- 94

  Fly   111 LPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNA--GANEKKLPVIVFIHGE 173
               :|:.||    |.....:.||..||.:. .||||||||:::|.:|  |:|   |||:|:|||.
  Rat    95 ---LQDITA----MNMQAFKLLKLTLPLIP-MSEDCLYLNIYTPNHAHEGSN---LPVMVWIHGG 148

  Fly   174 SFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQ 238
            :......:.||||:||:...|||||:.||||:|||.:....   ||| .|:|.:||:|||||:||
  Rat   149 ALVIGMASLYDGSMLAAMENVVVVTIQYRLGVLGFFSTGDQ---HAR-GNWGYLDQVAALHWVQQ 209

  Fly   239 NIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSA-YSSWALVEDPVLFAIK 302
            ||..|||:|:.||:.|...|...::..:.|| |.|||||.||:.||.| .||...|...|::. .
  Rat   210 NIAHFGGNPDRVTIFGESAGGTSVSSHVVSP-MSRGLFHGAIMESGVALMSSLISVSSDVVYR-T 272

  Fly   303 LAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLDID 367
            :|....|...|.     :.:|:|||....|:: ::..:|...::..   |||:.: |.|..
  Rat   273 VANLSGCEQVDS-----KALVNCLRGKSEEEI-MSINKAFRIISGI---VDGIFL-PRHPK---- 323

  Fly   368 DLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLF 432
            :|:|      |||  |.....                                          :.
  Rat   324 ELLA------SAD--FHPIPS------------------------------------------II 338

  Fly   433 GVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFY------TIVNEYTDWDRTS 491
            ||...|..|...:.....    :.:.|:.|..|:......:.::.:      .::.||..   .|
  Rat   339 GVNNDEYGWIIPSSMTTT----DSKKKMDRQMVQAILQKRVAQMMWPPEFSDLLLEEYMG---DS 396

  Fly   492 QHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGR 556
            :.|...:......:.|..||.|.::......:|:|
  Rat   397 EDPQFLQVQFKEMMEDFTFVIPALQVAHFQRSNAP------------------------------ 431

  Fly   557 CYFYVFDYQT---KDGDYPQRMGTVHGEDLPYIF----GAPLVDGFSHFPQNYTKSETALSEAVM 614
            .|||.|.::.   ||.. |..:...||:::.:||    |...||        .|:.|..||..:|
  Rat   432 VYFYEFQHRPSFFKDSK-PPHVKADHGDEILFIFRSFWGGTQVD--------LTEEEELLSRRMM 487

  Fly   615 IFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLH-QKYLEIGMKPRIKNHFRAHQL 678
            .:|.||||.||||     ...||.           |..:|  | ::||::..:|.:....:|.:|
  Rat   488 KYWANFARQGNPN-----SEGLPY-----------WPVFD--HDEQYLQLDTQPAVGRALKAKRL 534

  Fly   679 SIWLRLIPELHRAGMEDVIARH 700
            ..|.:.:||..|. ::|...||
  Rat   535 QFWTKTLPEKIRE-LKDTEDRH 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	182/651 (28%)
Ces2h	NP_001037723.1	COesterase	30..537	CDD:278561	182/651 (28%)
		Aes	<127..>230	CDD:223730	52/109 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810