Protein Alignment Nlg4 and LOC4576565

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_061502644.1
• Gene: LOC4576565 / 4576565
• VectorBaseID: AGAMI1_007129
• Length: 578
• Species: Anopheles gambiae
• Alignment Length: 678
• Identity: 167/678 - (24%)
• Similarity: 256/678 - (37%)
• Gaps: 204/678 - (30%)

  Fly    70 FLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPV--CPQRLPNIQNETAALEKMPKGRLEYL 132
            |.|:|||.||..:|||.|   |.|     ::...:.|  |     :.:.:|...:.
Mosquito    56 FRGIPYAEPPVGENRFQP---PVP-----VTKFVTSVLDC-----STERDTCVAKN--------- 98

  Fly   133 KRLLPFLENQ----SEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNP--YDGSVLASY 191
                ||  ||    ||:||:|||::| .....:..|||:|||||.:|::.|||.  |....|...
Mosquito    99 ----PF--NQQWQGSENCLHLNVYTP-QMNRPDAPLPVMVFIHGGAFKYGSGNSDCYSPEYLLEQ 156

  Fly   192 GEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHG 256
             .|||||.|||||.||||:. |:....   .|..|.||:..|.|:..||..|.|||::|||.|..
Mosquito   157 -NVVVVTFNYRLGPLGFLHL-PSQGIE---GNAALHDQLLVLRWVADNIAHFNGDPHNVTLFGES 216

  Fly   257 TGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQ 321
            .||..::..:.|| :....||:||..|..|.:.:|:..|.:..:.:||:.:|.:...|     .:
Mosquito   217 AGAVSVHLHLLSP-LSTPFFHKAICESSVALADYAVPNDTLGNSRRLAQLLNPSAHSD-----AE 275

  Fly   322 IVDCLRDVPLEDL-------YLADIQAPNFLTSFGPSVDGVV---IRPGH--SNLDIDD------ 368
            :|:.||..|.:.|       .:.:.:..:.:..|.|.||...   |.|.|  ..|.||.
Mosquito   276 MVETLRSAPAQRLAELCDRTAIGEEKRGSIIMPFRPVVDQSAKEPIVPLHPIKALGIDGRIPAIP 340

  Fly   369 -LMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLF 432
             |:..|:|.                                  ||.|                |.
Mosquito   341 LLLGYNNRE----------------------------------GGSF----------------LT 355

  Fly   433 GVVTGESIWRFSAH-------DIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRT 490
            .::....:::....       |:.:| ..|.:| :.|..  .|:.:....:.:..|||..|
Mosquito   356 HILKHPELYQADLERIIPRTIDVTHG-TPEAKD-LARAI--EAFYFGPEGLSHRKVNECAD---- 412

  Fly   491 SQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSG 555
                         .:||..|.. ::|....:.|.                          .|...
Mosquito   413 -------------LMSDFSFTI-LMRVTAEMHAR--------------------------YQHRS 437

  Fly   556 RCYFYVFDYQTKDGDYPQRM-----GTVHGEDLPYIFGAPL----VDGFSHFPQNYTKSETALSE 611
            ..:||.|:|..:...|.:.:     |..|.::|.|:|...:    |.     ||:.   |..:..
Mosquito   438 PLFFYRFEYDGELNQYKKFLPFPIAGAYHADELGYLFRMRMRPKEVQ-----PQSV---EARVRR 494

  Fly   612 AVMIFWTNFARTGNPNEHHRQDSSL-----PVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKN 671
            .:...||||||.|||...|  |.||     ||.       ::..::..|.|..||.|..:|.:..
Mosquito   495 YMCRMWTNFARYGNPTPPH--DESLCFGWTPVP-------TLEPDSTAPFHLPYLRINGEPEMAL 550

  Fly   672 HFRAHQLSIWLRLIPELHRAGMEDVIAR 699
            .....::..| |.|.:....|....:|:
Mosquito   551 DPDKERIDFW-RQIYDKFNGGFHKPVAK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	162/658 (25%)
LOC4576565	XP_061502644.1	None