Protein Alignment Nlg4 and LOC4576532

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_556011.3
• Gene: LOC4576532 / 4576532
• VectorBaseID: AGAMI1_011044
• Length: 564
• Species: Anopheles gambiae
• Alignment Length: 667
• Identity: 167/667 - (25%)
• Similarity: 261/667 - (39%)
• Gaps: 182/667 - (27%)

  Fly     1 MGESQLLLLLRLLLLPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLR 65
            ||.|:||..|.|      .|:.:....::||          .||..:.|.:.|        ....
Mosquito     1 MGTSRLLAALCL------AIACITIEASTTA----------TIVHLKNGPIAG--------ERRG 41

  Fly    66 SVEVFLGVPYATPPTKQNRFSPTRA-PAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRL 129
            ....|.|:|||.||..:.||:.:.. ...|...|.:....|||.|
Mosquito    42 DYYAFEGIPYAKPPLGKLRFAASEMNDDRWTEPRNATVRGPVCLQ-------------------- 86

  Fly   130 EYLKRLLP---FLENQSEDCLYLNVFS-PVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLAS 190
              ...|:|   .||. :||||:|||:: .::..|   :||.|.||||.:..:.:||.|:...:..
Mosquito    87 --WNHLIPGDNKLEG-TEDCLFLNVYTRSIDPTA---RLPTIAFIHGGALMFGTGNFYEPDHIMR 145

  Fly   191 YGEVVVVTLNYRLGILGFLNANPN--PHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLA 253
             .::::||.|||||.||||:...:  |      .|:||.||:.||.||::||:.|||||.:|::.
Mosquito   146 -RQMILVTFNYRLGPLGFLSTEDDVIP------GNFGLKDQVIALQWIRENIESFGGDPETVSIV 203

  Fly   254 GHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRH 318
            |:..|:|.::....|| :.||||...|..||||.:.|.::|..|..||::...:.|.     .|.
Mosquito   204 GYSAGSASVHLHYLSP-LSRGLFTSGIGHSGSALNPWVMMERSVEKAIRIGAVLGCP-----TRK 262

  Fly   319 HEQIVDCLRDVPLEDLYLADIQAPNFL----TSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSA 379
            .:.::||||..|.||:..   |.|.||    ..|.| ...||.:.|..|   .....:.:.||..
Mosquito   263 TQALLDCLRKQPAEDIVR---QVPQFLDYLYNPFSP-FGAVVEKKGPLN---PHPFLQETPRSLM 320

  Fly   380 DSG---------FQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVV 435
            .||         ..:.|.|                  .:.|..|.........:...:|.|...:
Mosquito   321 SSGNIAKVPLILSVTEAEG------------------LYPGAEFISDPKYLQELDARWDELVPSI 367

  Fly   436 TGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDT 500
            ..   ::.|..|      .:.||::... :||.| :..||             |.|   :....|
Mosquito   368 LD---YKTSVPD------PKARDRLSEA-IRNHY-FGPNE-------------RLS---LENFKT 405

  Fly   501 AVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQ 565
            .:..:|:..:.|.:..:..::                              .|....|.|...|:
Mosquito   406 LIRIISNRLYFAGVTESAKLM------------------------------HPFTNVYVYYDLYK 440

  Fly   566 TKDG--------DYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFAR 622
            :|.|        |.|..:|..||:|:..||.:.|.:   ..|  :|:.|..:.:..:..:.:||:
Mosquito   441 SKFGVGEALSHRDEPGLLGVAHGDDVLLIFPSVLRE---EVP--FTEEEMQVVDRFVTMYEHFAK 500

  Fly   623 TGNPN----EHHRQDSS 635
            ...|.    |...|||:
Mosquito   501 GDQPRFGAYELPLQDST 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	157/625 (25%)
LOC4576532	XP_556011.3	None