Protein Alignment Nlg4 and alpha-Est3

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001163540.1
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 674
• Identity: 174/674 - (25%)
• Similarity: 249/674 - (36%)
• Gaps: 229/674 - (33%)

  Fly    70 FLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKR 134
            |..:|||.||....||.......||     |.......|.:.|...|             .|.|:
  Fly    29 FERIPYAQPPVGHLRFMAPLPVEPW-----SQPLDCTKPGQKPLQFN-------------HYSKQ 75

  Fly   135 LLPFLENQSEDCLYLNVF-----SPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASY--- 191
            |     ...||||||||:     ||       :.||:|||..|..||  .|:|........|
  Fly    76 L-----EGVEDCLYLNVYAKELDSP-------RPLPLIVFFFGGGFE--KGDPTKELHSPDYFMM 126

  Fly   192 GEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHG 256
            .:|||||::||:|.||||:.| :| |.....|.||.||:.|:.||::|.::|.|||.:||..|..
  Fly   127 RDVVVVTVSYRVGPLGFLSLN-DP-AVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGES 189

  Fly   257 TGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWAL--VED-PVLFAIKLAKEVNCTIPDDINRH 318
            .|||.::|||.:| ...||||:|||.||:...||||  ::: |...|:.|..|....:.|
  Fly   190 AGAASVHYLMLNP-KAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMESAEHVTD----- 248

  Fly   319 HEQIVDCLRDVPLEDL---YL--ADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSS 378
             ..::|.|:.:|.|.|   ||  |:....:.:..|||.|:  ..:..|..|.       |..:..
  Fly   249 -AMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVE--PYKTEHCALP-------NHPQEL 303

  Fly   379 ADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRF 443
            .|..:                                         |....||   ::|.|
  Fly   304 LDKAW-----------------------------------------GNRIPVL---MSGTS---- 320

  Fly   444 SAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQH--PINTRDTAVAALS 506
                    |||      :..|.|.....:|          .|...:..:|  |::.:.....||:
  Fly   321 --------FEG------LLMYARVQMAPYL----------LTSLKKEPEHMLPLDVKRNLPQALA 361

  Fly   507 --------DAQFVAPIVRAGDILAANSPPPVSSSS-------------------TAGSPGANAAA 544
                    :..|           ..|.|..:|..|                   |..|...:::|
  Fly   362 RHLGQRLQETHF-----------GGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRSRVKSSSA 415

  Fly   545 STSAGSTQPSGRCYFYVFDYQTKDGDYPQRM--------GTVHGEDLPYIFGAPLVDGFS----- 596
            ||           |.|.||:.:...:: ||:        |..|.:|..|::    ...||
  Fly   416 ST-----------YLYRFDFDSPTFNH-QRLKYCGDKLRGVAHVDDHSYLW----YGDFSWKLDK 464

  Fly   597 HFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQK-- 659
            |.|:..|      .|.::...|:||||.|||....|| .||.:||        |:   ||:.|
  Fly   465 HTPEFLT------IERMIDMLTSFARTSNPNCKLIQD-QLPRAKE--------WK---PLNSKSA 511

  Fly   660 --YLEIGMKPRIKNHFRAHQLSIW 681
              .|.|....::.......:|.:|
  Fly   512 LECLNISENIKMMELPELQKLRVW 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	173/672 (26%)
alpha-Est3	NP_001163540.1	Abhydrolase	3..529	CDD:304388	172/666 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900