Protein Alignment Nlg4 and alpha-Est5

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 625
• Identity: 157/625 - (25%)
• Similarity: 245/625 - (39%)
• Gaps: 196/625 - (31%)

  Fly    54 LILPLDSFRFLRSVEV-------FLGVPYATPPTKQNRFSPTRAPA---PWDGIRISDKYSPVCP 108
            |.||:...:.::.:.:       |..:|:|.||..:.||   |||.   ||.|:.....|:....
  Fly    13 LTLPVGQIKGVKRLSLYDDPYFSFEKIPFAKPPLGELRF---RAPVPADPWSGVLDCTHYAEKPT 74

  Fly   109 QRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGE 173
            ||        ..|.:..:|               .||||||||:|  ....:||.|||:|:|:|.
  Fly    75 QR--------GLLTREIEG---------------GEDCLYLNVYS--KQLKSEKPLPVMVYIYGG 114

  Fly   174 SFEWSSGNPYDGSVLASYG-------EVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMA 231
            :|....      :....||       :||:||||||:..||||:.. :|.... ..|.||.||:.
  Fly   115 AFTVGE------ATRELYGPDYFMTKDVVLVTLNYRVDCLGFLSLK-DPSLKV-PGNAGLKDQVL 171

  Fly   232 ALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWA--LVE 294
            ||.|::|.|..|.||.:::|:.|...| .|..:.|......|||||:||.|||:.::.||  ..|
  Fly   172 ALKWVKQYISNFNGDDSNITVFGESAG-GCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAE 235

  Fly   295 DPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAP-----NFLTSFGPSV-- 352
            |   ||.:||::...|..:|    ..::::.|:.||..||...::..|     ..|.:|||:|
  Fly   236 D---FAFRLAQQNGFTGEND----DAKVLEYLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEA 293

  Fly   353 ----DGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGY 413
                |.||.:|...       |||::
  Fly   294 YVGEDCVVPKPPVE-------MARDA--------------------------------------- 312

  Fly   414 FGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFY 478
                      ...::.|:.|   |.|            |||        .::..|.:.:|..:
  Fly   313 ----------WSNNFPVMLG---GTS------------FEG--------LFMYPAVSANLKAL-- 342

  Fly   479 TIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGS------ 537
                :....|.|...|::.| |..:...:.::...:::|   ....|||  ||......
  Fly   343 ----DSLSQDPTRLVPVDVR-TVSSEKENLEYSQRLMKA---YFGYSPP--SSELLLNMLDFYSY 397

  Fly   538 ----PGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQ--------RMGTVHGEDLPYIF--- 587
                .|.|  .:.:|..|......|:|.||:.:.:.::.:        :.|..|.:||.|:|
  Fly   398 KIFWHGFN--RTFNARLTYAKAPTYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSYLFRNA 460

  Fly   588 GAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPN 627
            |:..:|        .|.:|....|.::..||.||.|.|||
  Fly   461 GSWKLD--------KTSAEYRTIERMIGIWTAFAATSNPN 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	157/625 (25%)
alpha-Est5	NP_001246965.1	alpha/beta hydrolases	12..533	CDD:473884	157/625 (25%)