Protein Alignment Nlg4 and alpha-Est8

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 152/662 - (22%)
• Similarity: 247/662 - (37%)
• Gaps: 207/662 - (31%)

  Fly    43 IVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVC 107
            |..|.||::.|  :...|. :..:...|.|:|:|.||..:.||.....|..|..::
  Fly    34 IADTVYGKVKG--VKWQSI-YGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVK--------- 86

  Fly   108 PQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFS----PVNAGANEKKLPVIV 168
              |..:::.:...:..:       ||::     ..|||||||||::    |      .:.|||:|
  Fly    87 --RCTHVRAKPCQVNIV-------LKQV-----QGSEDCLYLNVYTRELHP------HRPLPVLV 131

  Fly   169 FIHGESFEW--SSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARV---ANYGLMD 228
            :|:|..|:.  :|.:.|....: ....||:|.::||||.||||:.     |...:   .|.||.|
  Fly   132 WIYGGGFQMGEASRDLYSPDYI-MMEHVVLVVISYRLGALGFLSL-----ADEELDVPGNAGLKD 190

  Fly   229 QMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALV 293
            |:.||.|:::|.|.|||||:::|:.|...|.|..:|:|.: ...:||||:.|:|||||.:.||..
  Fly   191 QVMALRWVKRNCQFFGGDPDNITVFGESAGGASTHYMMLT-DQAKGLFHKTIIMSGSALAPWAQT 254

  Fly   294 EDPVLFAIKLAKEVNCT---IPDDINRHHEQIVDCLRDVPL---EDLYLADIQAPNF-LTSFGPS 351
            ...:.:..:||:....|   ...||..|   :..|.....|   ||:...:.:.... :.||||:
  Fly   255 PTHINWPYRLAQATGYTGDANDRDIFAH---LKKCKASSMLKVAEDIITMEERHQRLTMFSFGPT 316

  Fly   352 VDGVVIRPGHSNLDIDDL-MARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFG 415
            :: ..:.| |..:....| |.|:.                          .|.......||..|.
  Fly   317 IE-PYLTP-HCVIPKSPLEMMRDC--------------------------WGNSIPMVIGGNSFE 353

  Fly   416 GSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFY-- 478
            |.            ::|..|...........|.:|   ...:|..:....|.|:...:.|:::
  Fly   354 GL------------LMFPEVNKWPELLCQLGDCEN---LAPQDAHVDEQQRKAFGKKVRELYFGD 403

  Fly   479 ------TIVNEYTD-------WDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVS 530
                  ||: ||:|       |     |.|:.     ..||.|...
  Fly   404 RTPGRKTIL-EYSDLFSYKYFW-----HGIHR-----TLLSRAHHA------------------- 438

  Fly   531 SSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRM-------GTVHGEDLPYIFG 588
                                  |....:.|.||:.:|..:..:.:       ||.|.:||.|:|
  Fly   439 ----------------------PLAPTFLYRFDFDSKHFNIMRIITCGRKVRGTCHADDLSYLF- 480

  Fly   589 APLVDGFSHFPQNYTKSETALSEAVMIFWT---------NFARTGNPN--------EHHRQDSSL 636
                         |..:...|......|.|         :||.:|:||        :...:.:.|
  Fly   481 -------------YNAAAKKLKRRTAEFKTIKRLVSMVVHFAISGDPNIPMVCQDEKEQPRGAWL 532

  Fly   637 PVSKERNRFRSI 648
            |:||:...|:.:
  Fly   533 PISKDDKVFQCL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	152/662 (23%)
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	152/662 (23%)
		Aes	<116..>221	CDD:223730	40/116 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810