Protein Alignment Nlg4 and alpha-Est10

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 169/662 - (25%)
• Similarity: 260/662 - (39%)
• Gaps: 181/662 - (27%)

  Fly     8 LLLRLLLLPTVLISWMHCAGASTADI----YKGARLG---HRIVQTRYGRLHGL----ILPLDSF 61
            ||....|:|...:..:...|.....:    |:..:|.   :.:::|:.|.:.|:    |.....|
  Fly     8 LLRHFSLIPNKSVPKVFTNGDFIQQVISFKYEQRKLSTAIYSVIKTKSGPVRGVKRNTIWGGSYF 72

  Fly    62 RFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPK 126
            .|.:       :|:|.||....||....|..|||             |.|    :.|:..:|..:
  Fly    73 SFEK-------IPFAKPPVGDLRFKAPEAVEPWD-------------QEL----DCTSPADKPLQ 113

  Fly   127 GRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFE--WSSGNPYDGSVLA 189
            ..:.:.|..      .|||||||||:  |.....:|..||:|:|:|..::  .:|.:.|......
  Fly   114 THMFFRKYA------GSEDCLYLNVY--VKDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFM 170

  Fly   190 SYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAG 254
            | .:||:||:.||||.||||:.: :|..:. ..|.||.||:.||.|:||||:.||||.|::||.|
  Fly   171 S-KDVVIVTVAYRLGALGFLSLD-DPQLNV-PGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFG 232

  Fly   255 HGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDP-VLFAIKLAKEVNCTIPDDINRH 318
            ...|.|..::|..|| ...||.|:||:||||....|  .:.| ..:|.:||:::..|    .:..
  Fly   233 ESAGGASTHFLALSP-QTEGLIHKAIVMSGSVLCPW--TQPPRNNWAYRLAQKLGYT----GDNK 290

  Fly   319 HEQIVDCLRDVPLEDLYLA-------DIQAPNFLTSFGPSVD------GVVIRPGHSNLDIDDLM 370
            .:.|.:.||.:...::..|       |.:....|.:|||.|:      .||.:..|      :||
  Fly   291 DKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPH------ELM 349

  Fly   371 ARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYF---GGSGAGTMNMGGHYDVLF 432
             :||........|                     .|:||.|..|   ......|::..|:...|.
  Fly   350 -QNSWSHRIPMMF---------------------GGTSFEGLLFYPEVSRRPATLDEVGNCKNLL 392

  Fly   433 GVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINT 497
                        ..|:....:.:.|:.         |...|.:.::            ...|.|.
  Fly   393 ------------PSDLGLNLDPKLREN---------YGLQLKKAYF------------GDEPCNQ 424

  Fly   498 RDTA--VAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFY 560
            .:..  :...|..:|..||.||                     ..|....:||.:       |.|
  Fly   425 ANMMKFLELCSYREFWHPIYRA---------------------ALNRVRQSSAPT-------YLY 461

  Fly   561 VFDYQTK---------DGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKS-ETALSEAVMI 615
            .||:.:|         .|.  |..|..||:||.|||.:.|    ||  |:...| |..:...::.
  Fly   462 RFDHDSKLCNAIRIVLCGH--QMRGVCHGDDLCYIFHSML----SH--QSAPDSPEHKVITGMVD 518

  Fly   616 FWTNFARTGNPN 627
            .||:||..|:||
  Fly   519 VWTSFAAHGDPN 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	162/620 (26%)
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	162/621 (26%)
		Aes	<132..>279	CDD:223730	61/154 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810