Protein Alignment Nlg4 and Est-6

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 675
• Identity: 158/675 - (23%)
• Similarity: 228/675 - (33%)
• Gaps: 233/675 - (34%)

  Fly    10 LRLLLLPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVP 74
            |.|:::.:.|  |:....:.|.|        ..:||...|:|.|        |...|...:..:|
  Fly     6 LGLIIVLSCL--WLGSNASDTDD--------PLLVQLPQGKLRG--------RDNGSYYSYESIP 52

  Fly    75 YATPPTKQNRFSPTRAPAP----WDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRL 135
            ||.|||...||   .||.|    |..|..:.|....|.|           .::...|..:.:
  Fly    53 YAEPPTGDLRF---EAPEPYKQKWSDIFDATKTPVACLQ-----------WDQFTPGANKLV--- 100

  Fly   136 LPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESF----EWSSGNPYDGSVLASYGEVVV 196
                  ..||||.::|:.|.|:..|  ..||:..|||.:|    .|.:|:.   :|:.. |:.::
  Fly   101 ------GEEDCLTVSVYKPKNSKRN--SFPVVAHIHGGAFMFGAAWQNGHE---NVMRE-GKFIL 153

  Fly   197 VTLNYRLGILGFLNANPN--PHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGA 259
            |.::||||.|||::....  |      .||||.||..||.||:|||..|||:|.:|.|.||..|.
  Fly   154 VKISYRLGPLGFVSTGDRDLP------GNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGG 212

  Fly   260 ACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVD 324
            |.::..|......: |...|...||:|...|.:.:.....|.:|.:.|.|...:|    ...:..
  Fly   213 ASVHLQMLREDFGQ-LARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAED----STSLKK 272

  Fly   325 CLRDVPLEDLYLADIQAPNFL-------TSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSG 382
            ||:..|..:|..|   ...||       ..|.|     |:.|.    |..|.:.....|....||
  Fly   273 CLKSKPASELVTA---VRKFLIFSYVPFAPFSP-----VLEPS----DAPDAIITQDPRDVIKSG 325

  Fly   383 FQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHD 447
                                                            .||.|.    |..|...
  Fly   326 ------------------------------------------------KFGQVP----WAVSYVT 338

  Fly   448 IQNGFEG-----ERRDKIIRTYVRNAYNYHLNE---------IFYTIVNEYTDWD----RTSQHP 494
            ...|:..     ||:..|:..        .|||         :||.......|.|    :..|..
  Fly   339 EDGGYNAALLLKERKSGIVID--------DLNERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEY 395

  Fly   495 INTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPS----- 554
            |..:...:.:.|:.|.:..     |||..|                         |||.|
  Fly   396 IGNQRFDIESYSELQRLFT-----DILFKN-------------------------STQESLDLHR 430

  Fly   555 --GR--CYFYVFDYQTKDG---------DYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTK-- 604
              |:  .|.||:|...:.|         ||.  .|||||:|...||            :|:.:
  Fly   431 KYGKSPAYAYVYDNPAEKGIAQVLANRTDYD--FGTVHGDDYFLIF------------ENFVRDV 481

  Fly   605 ----SETALSEAVMIFWTNFARTGN 625
                .|..:|...:....:||.:.|
  Fly   482 EMRPDEQIISRNFINMLADFASSDN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	152/642 (24%)
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	152/642 (24%)
		Aes	<110..>243	CDD:223730	52/145 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810