Protein Alignment Nlg4 and Jhedup

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 168/673 - (24%)
• Similarity: 263/673 - (39%)
• Gaps: 180/673 - (26%)

  Fly    49 GRLHGLILP-LDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLP 112
            |.:.|.::| ..|..|    |.|:|:|:|.||....|........||:|:..:......|.||
  Fly    28 GCMRGTLMPGYQSGEF----EAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQR-- 86

  Fly   113 NIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEW 177
                             .|..:....:  ..||||||||:.|.|..  |.||||:|:|||..|..
  Fly    87 -----------------SYFAKEWGLM--GVEDCLYLNVYRPKNRA--EDKLPVMVYIHGGGFFS 130

  Fly   178 SSGNPYDG--SVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNI 240
            .|.:|...  ..|....:||:||:|||||..|||:.. :.|   ...|:|..||..||.|||::|
  Fly   131 GSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTG-DEH---MPGNFGFKDQRLALQWIQKHI 191

  Fly   241 QKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAY-SSWALVEDPVLFAIKLA 304
            ..|||||..||:.||..|....:..|.||.. :|||..::.::|:.: |:..:::||:..|.:|.
  Fly   192 ATFGGDPKKVTVLGHSAGGISAHLHMISPNS-KGLFQNSMSLTGTMFLSAMKILKDPLSQARRLG 255

  Fly   305 KEVNCTIPDDINRHHEQIVDCLRDV-PLEDLYLADI-----QAPNFLTSF----GPSVDGVVI-- 357
            ||:.....:.::  .:.:.:.||:| |.:.|...|.     ..|: ||:.    .||.|..::
  Fly   256 KELAIDQAESLS--SQDLAEALRNVCPKKLLVSVDSLKVWDNMPH-LTTLPVLEAPSPDAFLVED 317

  Fly   358 -----RPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGG- 416
                 |.|..| .:..:::.:||                           .|.||.|....|..
  Fly   318 PLDAHRAGRIN-QMPWILSLSSR---------------------------AGEGSLFIMRAFINP 354

  Fly   417 --SGAGTMNMGGHYDVLFGVVTGESIWRFS----AHDIQNGFEGE--RRDKIIR-TYVRNAYNYH 472
              ......|...|..:|..:..|..:...|    |:|    |:|:  ..|.::: ..:...:|::
  Fly   355 KLRAEFNENFLEHMALLLNLPEGTPVQMVSEILDAYD----FKGDSLNNDTMLKLAEISGDFNFY 415

  Fly   473 LNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGS 537
            ..  .|..::.|..:....::|:              |:.....|
  Fly   416 YP--IYETISSYVTYANLEENPL--------------FIYIFEFA-------------------- 444

  Fly   538 PGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNY 602
             |.|:.....||:|...|                   :|.||.:|..:....|:  .|..||::
  Fly   445 -GLNSITKFFAGTTDDYG-------------------LGAVHMDDGLHTIRIPV--SFDDFPKD- 486

  Fly   603 TKSETA-LSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLH-----QKYL 661
              ||.| :.:.:....|:||:||..:|    :|...||.    |:.....||  ||     :|||
  Fly   487 --SEDAKVIQRMSSLMTDFAKTGVFHE----ESICKVSD----FKEQGMCNY--LHFGGNKEKYL 539

  Fly   662 EIGMKPRIKNHFRAHQLSIWLRL 684
            |     .|:|........||.:|
  Fly   540 E-----DIRNSITLTAFPIWKKL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	165/668 (25%)
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	148/604 (25%)
		Aes	<106..>210	CDD:223730	48/109 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810