Protein Alignment Nlg4 and Gli

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Alignment Length: 934
• Identity: 232/934 - (24%)
• Similarity: 354/934 - (37%)
• Gaps: 255/934 - (27%)

  Fly    16 PTVLISWMH-CAGASTADIYKGARLGHRIVQTRYGRLHGLILPL------DSF---------RFL 64
            |.||..|.. ..|....|.....|  ...|.|.||::.|..:.:      .||         |.:
  Fly   110 PGVLAGWREDLQGKQRRDSLTLER--DVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVM 172

  Fly    65 RSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRL 129
            ....||||:|||.|||.:.||.|.|....|..::..| :.|.|||.:    ..|.|    .||
  Fly   173 GECSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQAVD-FGPACPQPV----RYTGA----TKG-- 226

  Fly   130 EYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEV 194
                     :.:..||||||||:||.......:|.||:|:|||..|...:.|.:.|.:|||:.:|
  Fly   227 ---------IMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDV 282

  Fly   195 VVVTLNYRLGILGFLNANP--NPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGT 257
            ||||||||||.||||:...  :|      .|||::||..||.|:..||:.|.||.||:||.|.|.
  Fly   283 VVVTLNYRLGALGFLSTGDENSP------GNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGA 341

  Fly   258 GAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVL---FAIKLAKEVNCTIPDDINRHH 319
            |.|....||.:| ..|.:..|.|..||||.:.|||::|...   .:..|.:.:.|:|...
  Fly   342 GGASAGLLMVAP-QTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESS----- 400

  Fly   320 EQIVDCLRDVPLEDLY-LADIQAPNFLTSF--GPSVDGVVIRPGHSNLDIDDLMARNSRRSSADS 381
            .::|:|||..  ...| |.:.:....:.||  ||.:|.....||      ||
  Fly   401 WKLVNCLRTG--RSFYELGNAEFSPQVGSFPWGPVLDHNFTLPG------DD------------- 444

  Fly   382 GFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGG----------------SGAGTMNMGGHYDV 430
                                           ::.|                ..||..|....|
  Fly   445 -------------------------------WYEGWREKDWRFLTQTPETLIRAGKFNRNIQY-- 476

  Fly   431 LFGVVTGESIWRFSAHDIQNGF---EGERRDKIIRTYVRNAYNYHLNE--IFYTIVNEYTDWDRT 490
            :.||.|.|:.:..:.::..:.:   :|...|:.||.:|.. |||.||.  ::..|...||.|...
  Fly   477 MTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFR-YNYTLNPNGVYEAIKYIYTFWPDP 540

  Fly   491 SQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSG 555
            :.:.| .||..:..|||..:.||:.:...::.....|
  Fly   541 NNNTI-IRDQYINMLSDLYYRAPVDQMVKLMLEQKVP---------------------------- 576

  Fly   556 RCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQN-------YTKSETALSEAV 613
             .|.||.:...:..:.||.....|..:..::.|||.:| ...||:.       :|.::..:|...
  Fly   577 -VYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPFMD-TEFFPKKEHLQRNMWTDNDRNMSHFF 639

  Fly   614 MIFWTNFARTGNP---------------------NEHHRQDSSLPVSKERNRFRSIT-------- 649
            |..:|||||.|||                     |.:...:||:.::..:......|
  Fly   640 MQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVIG 704

  Fly   650 -------------WENYDPLHQKYLEIGM----------------KPRIKNHFRAHQLSIWLR-- 683
                         ||..:||...:..:.:                :...:...|.:...:::.
  Fly   705 VLVPTYPPTTEYWWEPKEPLQIAFWSMSVACFFLIVLVVICCIMWRNAKRQSDRFYDEDVFINGE 769

  Fly   684 -LIPELHRAGMED--VIARHNLFRNHDDMDLYEGPVKPDPFGISTAAGASGSSSSSSSSSRLLLV 745
             |.||....|:::  ::..|:..|:.|  ::||  .:..|...:.|:.|...::|..|.|.|.:.
  Fly   770 GLEPEQDTRGVDNAHMVTNHHALRSRD--NIYE--YRDSPSTKTLASKAHTDTTSLRSPSSLAMT 830

  Fly   746 DE---QLMMKKGRGLNGSAYLNGILGVTTVEPNNMYTTCIPIGGNYSSSGGVFAPTT----LANA 803
            .:   |..:|.|..|..:   ||.|    |:.:....|  |......|:..|.:|..    |...
  Fly   831 QKSSSQASLKSGISLKET---NGHL----VKQSERAAT--PRSQQNGSTAKVASPPVEEKRLLQP 886

  Fly   804 SSDTLASGFEAAGYAAYSTALSVT 827
            .|.|..:..:|.......||.||:
  Fly   887 LSSTPVTQLQAEPAKRVPTAASVS 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	188/746 (25%)
Gli	NP_476602.1	COesterase	134..695	CDD:278561	182/678 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920