Protein Alignment Nlg4 and Ces5a

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001012056.2
• Gene: Ces5a / 307660
• RGDID: 1549717
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 688
• Identity: 186/688 - (27%)
• Similarity: 287/688 - (41%)
• Gaps: 175/688 - (25%)

  Fly    18 VLISWMHCA---GASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPP 79
            :.:.|:..|   |:.|.:.::..|||.  ||.:...:.|.:.|         |.||||:|:|.||
  Rat    13 IWVLWIFAAIIRGSVTEEPHRYTRLGW--VQGKQATVLGRLEP---------VNVFLGIPFAAPP 66

  Fly    80 TKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNI---QNETAALEKMPKGRLEYLKRLLPFLEN 141
            ....|||..:.|.||..:|.:..|..||.|.|..:   ||              .||...|.| .
  Rat    67 LGPLRFSNPQPPIPWHDLREATTYPNVCFQNLEWLFIYQN--------------LLKVHYPKL-G 116

  Fly   142 QSEDCLYLNVFSPVNAGANE-KKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGI 205
            .||||||||:::|  |.||: .:|||:::|.|..||..|.:.:|||.||:|.:|::||:.|||||
  Rat   117 VSEDCLYLNIYAP--AYANDGSRLPVMMWIPGGGFETGSASIFDGSALAAYEDVLIVTIQYRLGI 179

  Fly   206 LGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPT 270
            .||.|.. |.||   ..|:...||:|||.|:::||..|||:|:|||:.|...||..|:.|:.||
  Rat   180 FGFFNTQ-NQHA---PGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAISISSLILSP- 239

  Fly   271 MVRGLFHRAILMSGSA-YSSWALVEDPVLFAIKLAKEV-NCTIPDDINRHHEQIVDCLRD-VPLE 332
            :..|||||||:.||.| ..|....:|.:...:::..:| .|.:.|.     :.::.|||: ..||
  Rat   240 LSAGLFHRAIMQSGVAIIPSLKNFDDELKHGLQVVADVCKCNVSDS-----KVLLKCLREKSSLE 299

  Fly   333 DLYLADIQAPNFLTSFGPSVDGVVIRPGHSNL-------DIDDLMARNSRRSSADSGFQSSAGGG 390
            .|.|.     ....:|...|||.........|       .:..::..|::..
  Rat   300 LLSLG-----QKTKAFTRVVDGSFFPEEPMELLSQKTFKTVPSIIGVNNQEC------------- 346

  Fly   391 GGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGE 455
                                 ||.       :.|....::|||  :.||......|
  Rat   347 ---------------------GYI-------LPMREAPEILFG--SNESTALTLIH--------- 372

  Fly   456 RRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDI 520
                 :..::...|.:.:.:.::...:..||          .|||.:....|..||.|    |.:
  Rat   373 -----VLLHIPPQYMHIVAKDYFHGKHSLTD----------IRDTLLDLFGDVFFVVP----GLV 418

  Fly   521 LAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTK--DGDYPQRMGTVHGEDL 583
            .|.|       ...||.|                  .|||.|.::..  ....|..:...|.:::
  Rat   419 TARN-------HRDAGGP------------------VYFYEFQHRPNCFQNTRPAFVKADHTDEI 458

  Fly   584 PYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSI 648
            .::||.|.::|.....:..|:.|..||..:|.:|.||||:|:||     ...||:
  Rat   459 RFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFARSGDPN-----GDDLPL---------- 508

  Fly   649 TWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIP 686
             |..||. ::.||::.:........:..::..|...:|
  Rat   509 -WPAYDQ-NESYLKLDVNISTGWRLKDRRVEFWTDTLP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	177/653 (27%)
Ces5a	NP_001012056.2	COesterase	29..539	CDD:395084	180/665 (27%)