Protein Alignment Nlg4 and Ces4a

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001099646.1
• Gene: Ces4a / 291955
• RGDID: 1307418
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 686
• Identity: 194/686 - (28%)
• Similarity: 284/686 - (41%)
• Gaps: 193/686 - (28%)

  Fly    43 IVQTRYGRL----------HGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGI 97
            :|||..|.|          ||::...........:.||||||::.||....||:|...|.||:||
  Rat    21 VVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGI 85

  Fly    98 RISDKYSPVCPQRLPNIQNETAALEKM---PKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGA 159
            |.:..|.|.|      :|.....:..|   .:.:.|:|        :.|||||||||::||.| .
  Rat    86 RDATTYPPSC------LQESWGQITSMYLNTRKQYEWL--------HFSEDCLYLNVYAPVLA-P 135

  Fly   160 NEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANY 224
            .:..|||:|:..|.:|...|.:.|:||.||:.|:||:|.|.||||||||.:..   ::||| .|:
  Rat   136 GDPLLPVMVWFPGGAFLVGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTG---NSHAR-GNW 196

  Fly   225 GLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSS 289
            ||:||:|||.|:|:||:.|||||:||||.|...||..::.|:.|| :.:||||:||..||:|...
  Rat   197 GLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSP-LAQGLFHQAISQSGTAVLK 260

  Fly   290 WALVEDPVLFAIKLAKEVNCTIPDDINRHHEQ--IVDCLRDVPLEDLYLADIQAPNFLTS----- 347
            ..:..||:..|.|:|....|.       |:..  :|.||:.:|.|.:.|...:...|..:
  Rat   261 TFITHDPLKSAKKIAHLAGCD-------HNSTKIMVKCLKALPAEKVMLVSKKMTFFRANSHKDP 318

  Fly   348 ------FGPSVDGVV-------------IRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQ 393
                  ..|.|||:|             ::|      :..|:..||..
  Rat   319 KDIVWFLSPVVDGLVFPEDPVVLLTRGQVKP------VPYLLGVNSAE----------------- 360

  Fly   394 GGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGERRD 458
                                |..|....|.:..:..::......:.:|..|   |......|:..
  Rat   361 --------------------FEWSLPFLMKLQLNQRIMNKNYITKLLWSCS---ILLNITEEQIP 402

  Fly   459 KIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAA 523
            .:.|.|:.:|.::|             ||.....|.|:       .:.||.||...::|
  Rat   403 LVAREYLSDAISHH-------------DWKMFRNHLID-------LVGDATFVYATLQA------ 441

  Fly   524 NSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQ-----TKDGDYPQRMGTVHGEDL 583
                 ......||||                  .|.|.|.:.     .|    |:..|..||::|
  Rat   442 -----ARYHRDAGSP------------------VYLYEFKHHAPGIIVK----PRSDGADHGDEL 479

  Fly   584 PYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSI 648
            .|:||:|...|.|.      ..|...|..:|.:|.|||.||:||     |..||.
  Rat   480 SYLFGSPFSKGSSR------GEEKEFSLQMMKYWANFAHTGDPN-----DRELPY---------- 523

  Fly   649 TWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRL 684
             |..:|. .:|||::....|:....|..|::.|.||
  Rat   524 -WPRFDK-EEKYLQLDFDTRVGVKLREKQMTFWRRL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	191/681 (28%)
Ces4a	NP_001099646.1	COesterase	33..554	CDD:395084	186/669 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810