Protein Alignment Nlg4 and Ces2g

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001099645.1
• Gene: Ces2g / 291952
• RGDID: 1308358
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 708
• Identity: 193/708 - (27%)
• Similarity: 296/708 - (41%)
• Gaps: 191/708 - (26%)

  Fly     8 LLLRLLLLPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLG 72
            :|..||||      .:|..|..:.:       ...|..|..|::.|.:.....|:  ..|..|||
  Rat    13 VLFGLLLL------LIHVQGQHSPE-------SSPIRNTHTGQVQGKLTHSKDFK--SGVHTFLG 62

  Fly    73 VPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLP 137
            :|:|..|....||:|..||.||.|:|.....|.:|||   |::.....|::|        |..||
  Rat    63 IPFAKAPVGPLRFAPPEAPEPWSGVRDGTSQSNICPQ---NVRMNMEGLKEM--------KLTLP 116

  Fly   138 FLENQSEDCLYLNVFSPVNA--GANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLN 200
            .: :.||||||||:::|.:|  |::   |||:|:|||.:......:.||||:||:..:|||||:.
  Rat   117 PV-SMSEDCLYLNIYAPAHAHEGSH---LPVMVWIHGGALTVGMASMYDGSMLAATEDVVVVTIQ 177

  Fly   201 YRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYL 265
            ||||:|||.:...:   ||| .|:|.:||:|||.|:||||..|||:|:.||:.|...|...::..
  Rat   178 YRLGVLGFFSTGDH---HAR-GNWGYLDQVAALRWVQQNIAHFGGNPDCVTIFGESAGGLSVSSH 238

  Fly   266 MTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVP 330
            :.|| |.:|||||||:.||.|.....:.....:....:.|...|...|.     |.:|.|||...
  Rat   239 VVSP-MSKGLFHRAIMESGVALMPGTIFNFSEMVYQMVVKLSGCEAMDP-----ESLVHCLRGKS 297

  Fly   331 LEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSAD-------SGFQSSAG 388
            .|.:.:...:    .......|||..: |.|.    .:|:|      |||       .||.:...
  Rat   298 EEQITVISKE----FQMIPAVVDGEFL-PNHP----QELLA------SADFHPVPSIIGFNNDEY 347

  Fly   389 G-------GGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAH 446
            |       |..|                                    .:.| :|.|::..|...
  Rat   348 GWIVPKVIGSAQ------------------------------------TIKG-ITRENLQAFLKD 375

  Fly   447 DI-QNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQF 510
            .. |.....|..|.::..|:.:.      |...|:..::|:                 .:.|..|
  Rat   376 TAPQMMLPPECSDLLMEEYMGDI------EDPQTLQAQFTE-----------------MMEDFMF 417

  Fly   511 VAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQT---KDGDYP 572
            |.|.::......:::|                              .|||.|.:|:   || ..|
  Rat   418 VIPSLQVARFQRSHAP------------------------------VYFYEFQHQSSFLKD-IRP 451

  Fly   573 QRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLP 637
            ..:...||:::|::||:    .|.....|.|:.|..|:..:|.:|.||||.||||     .:|||
  Rat   452 PHVKADHGDEVPFVFGS----FFWGMKLNLTEGEKLLNRRMMKYWANFARYGNPN-----SNSLP 507

  Fly   638 VSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIP----ELHRA 691
            .           |..:| ..::||::..:|.:....:|.:|..|.:.:|    ||.|:
  Rat   508 Y-----------WPVFD-YDEQYLQLNTQPAVGRIQKARKLQFWTKTLPQKIEELKRS 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	181/657 (28%)
Ces2g	NP_001099645.1	COesterase	31..539	CDD:278561	181/668 (27%)
		Aes	<129..>232	CDD:223730	50/109 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810