Protein Alignment Nlg4 and cest-9.2

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 683
• Identity: 142/683 - (20%)
• Similarity: 238/683 - (34%)
• Gaps: 246/683 - (36%)

  Fly    42 RIVQTRYGRLHGLILPLD--SFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYS 104
            ::::|.|||:.|:....|  :.:::     |..||:|.||..:.||:|.:.|..|.|:..:.|||
 Worm    22 KVIETSYGRVRGITEWSDDNNHKYM-----FKSVPFAKPPIGKLRFAPPQYPDSWSGVLDASKYS 81

  Fly   105 PVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEK----KLP 165
            |.|   |.|     ::....|:             |:.||||||:|:|:      :||    |..
 Worm    82 PAC---LSN-----SSTTSTPQ-------------EHVSEDCLYINIFT------SEKCLRSKCA 119

  Fly   166 VIVFIHGESFEWSSGNPY-DGSVLASY--GEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLM 227
            |||:.||.::...|...: |..:|..|  .:|::.....|||:.|.|...|:.   ....|..:.
 Worm   120 VIVYFHGGAYNGDSATMFPDNFILERYVAEDVILAIPGVRLGVFGQLYFGPSA---LLTENLFMF 181

  Fly   228 DQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYL----MTSPTMVRGLFHRAILMSGSAYS 288
            |.:.||.::...|..|||||..||:.||.:|...:..|    ...|.:  .||.:.|::||:...
 Worm   182 DAVQALDFVHNEIPNFGGDPKQVTIMGHSSGGTLVEALGFSNSVDPDL--KLFQQIIVLSGTGMF 244

  Fly   289 SW--ALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVP----------LEDLYLADIQA 341
            .:  .||::..:.:.||.. .|.|..:..:.:..:|::|:|.:.          :||:|
 Worm   245 GFYDLLVDNSFIISEKLGC-FNGTQEERTDANIAEILECMRQIDGHEIVGMQKHMEDVY------ 302

  Fly   342 PNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSG 406
                                 .|....|:
 Worm   303 ---------------------KLTFKSLL------------------------------------ 310

  Fly   407 SSFGGGYFGGSGAGTMNMGGHYD----------VLFGVVTGESIWRFSAHDIQNGFEGERRDKII 461
                      .||..|.:.|..:          .:||..                 |.|.|:::.
 Worm   311 ----------RGAPFMELNGKIEKFRNSTSPRNAIFGTT-----------------EYEFRNEVE 348

  Fly   462 RTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSP 526
            |      |.|        |...:.|:    ::|:     |||...|           |.|..|..
 Worm   349 R------YLY--------ITTTFLDF----ENPV-----AVAQHFD-----------DELMQNMD 379

  Fly   527 PPVSSSSTA--GSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGA 589
            ..::..:.:  .|..|.::|..:||:.         |:.::|:...|     :.|..|:.|..|.
 Worm   380 TMINGDAVSIFVSAAAFSSAMANAGAD---------VYLFETRQWPY-----SFHVSDMQYFIGI 430

  Fly   590 PLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYD 654
                   |....:|.....|.........||.:||.|                    |..|.:.:
 Worm   431 -------HREVLHTHDMDILDSFYSKLLVNFTKTGAP--------------------SPEWNSLE 468

  Fly   655 PLHQKYLEI------GMKPRIKNHFRAHQLSIW 681
            |....|||:      |..|.:...:...::|.|
 Worm   469 PEKMNYLELRVDTRNGKGPVMLEGYHDKEVSFW 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	141/680 (21%)
cest-9.2	NP_741910.3	Abhydrolase	19..501	CDD:304388	141/681 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900