Protein Alignment Nlg4 and Ces1c

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_006255234.2
• Gene: Ces1c / 24346
• RGDID: 2571
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 665
• Identity: 181/665 - (27%)
• Similarity: 267/665 - (40%)
• Gaps: 165/665 - (24%)

  Fly    40 GH----RIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRIS 100
            ||    .:|.|..|::.|..:.|:.  |.:.|.||||||:|.||....||:|.....||..::.:
  Rat    20 GHPSSPPVVDTTKGKVLGKYVSLEG--FTQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNT 82

  Fly   101 DKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLP 165
            ..|.|:|.|        ...:.|:....|...|..:|.  ..||||||||::||.:...| .:||
  Rat    83 TTYPPMCSQ--------DGVVGKLLADMLSTGKENIPL--EFSEDCLYLNIYSPADLTKN-SRLP 136

  Fly   166 VIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQM 230
            |:|:|||........:||.|..|:::..|||||:.|||||.|..:....   |:| .|:..:||:
  Rat   137 VMVWIHGGGLIIGGASPYSGLALSAHENVVVVTIQYRLGIWGLFSTGDE---HSR-GNWAHLDQL 197

  Fly   231 AALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVED 295
            |||.|:|.||..|||:|:|||:.|...|...::.|:.|| :.:.||||||..||...::....::
  Rat   198 AALRWVQDNIANFGGNPDSVTIFGESAGGVSVSVLVLSP-LAKNLFHRAISESGVVLTTNLDKKN 261

  Fly   296 PVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPG 360
            ....|..:|....|.     |.....:|.|||.....:|....::..|  ||....:||||
  Rat   262 TQAVAQMIATLSGCN-----NTSSAAMVQCLRQKTEAELLELTVKLDN--TSMSTVIDGVV---- 315

  Fly   361 HSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMG 425
                     :.:.......:..|.:..                         |.  .|......|
  Rat   316 ---------LPKTPEEILTEKSFNTVP-------------------------YI--VGFNKQEFG 344

  Fly   426 GHYDVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRN-AYNYHLNE-IFYTIVNEYTDWD 488
            .....:.|.:..               ||...:|:..:.:|. :.|.:::| :...|:.:|.
  Rat   345 WIIPTMMGNLLS---------------EGRMNEKMASSLLRRFSPNLNISESVIPAIIEKYL--- 391

  Fly   489 RTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQP 553
            |.:..|...::..:...||..|..|.|...           .|...||:|
  Rat   392 RGTDDPAKKKELLLDMFSDVFFGIPAVLMS-----------RSLRDAGAP--------------- 430

  Fly   554 SGRCYFYVFDY----------QTKDGDYPQRMGTVHGEDLPYIFGAP-LVDGFSHFPQNYTKSET 607
               .|.|.|.|          ||..||        ||:::..:||.| |.:|.|       :.||
  Rat   431 ---TYMYEFQYRPSFVSDQRPQTVQGD--------HGDEIFSVFGTPFLKEGAS-------EEET 477

  Fly   608 ALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQK--YLEIGMKPRIK 670
            .||:.||.||.||||.||||     ...||           .|..||   ||  ||:||...:..
  Rat   478 NLSKLVMKFWANFARNGNPN-----GEGLP-----------HWPEYD---QKEGYLQIGATTQQA 523

  Fly   671 NHFRAHQLSIWLRLI 685
            ...:..:::.|..|:
  Rat   524 QKLKGEEVAFWTELL 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	177/652 (27%)
Ces1c	XP_006255234.2	COesterase	24..534	CDD:395084	177/655 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810