Protein Alignment Nlg4 and Ces2e

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001093947.1
• Gene: Ces2e / 192257
• RGDID: 621563
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 688
• Identity: 175/688 - (25%)
• Similarity: 281/688 - (40%)
• Gaps: 184/688 - (26%)

  Fly    43 IVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVC 107
            |..|..|::.|..:.:...:  ..|..|||:|:|.||....||:|...|.||.|:|....:..:|
  Rat    33 IRNTHTGQVRGSFVHVKDTK--SGVHTFLGIPFAKPPIGPLRFAPPEPPEPWSGVRDGTSHPAMC 95

  Fly   108 PQRLP--NIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFI 170
            .|.:.  |::|....:.:.|              .:.|||||||::::|.:. ..:..|||:|:|
  Rat    96 LQNIDGLNLENLKIKMSRSP--------------VSMSEDCLYLSIYTPAHT-HKDSNLPVMVWI 145

  Fly   171 HGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHW 235
            ||....|...:.||||:||:..:|||||:.||||||||.:....   ||| .|:|.:||:|||.|
  Rat   146 HGGGLCWGMASTYDGSMLAAIEDVVVVTIQYRLGILGFFSTGDE---HAR-GNWGYLDQVAALRW 206

  Fly   236 IQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFA 300
            :||||..|||:|:.||:.|...|...::..:.|| |.:||||.||:.||.|.....:.....:..
  Rat   207 VQQNIVHFGGNPDRVTIFGESAGGISVSSHVVSP-MSQGLFHGAIMESGVALLPNLISNTSEVIY 270

  Fly   301 IKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGH---- 361
            ..:|....|...|.     |.::.|||:...|::    :...|.:.:....|||..: |.|
  Rat   271 TMVANLSGCEPVDS-----EALMSCLREKSEEEM----LAINNIVRTISGVVDGKFL-PRHPLEL 325

  Fly   362 -SNLD---IDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTM 422
             :::|   :..::..||
  Rat   326 LASVDFHPVPSIIGINS------------------------------------------------ 342

  Fly   423 NMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRN-AYNYHL-NEIFYTIVNEY- 484
               ..|..:..::..:|..:            |...:.:|..::| |....| .|....::.||
  Rat   343 ---DEYGWIIPMLHPDSTMK------------EINRETMRAVLKNTAVQMMLPPECSDLLMEEYM 392

  Fly   485 --TDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTS 547
              |:..:|.|...|      ..:.|..||.|.::......:::|
  Rat   393 GDTEDSKTLQIQFN------EMMGDFIFVIPALQVAHFQRSHAP--------------------- 430

  Fly   548 AGSTQPSGRCYFYVFDYQT---KDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETAL 609
                     .|||.|.:|:   || ..|..:...||::|||:.|....|    ....:|:.|..|
  Rat   431 ---------VYFYEFQHQSNFLKD-IRPPHVKADHGDELPYVIGYLFWD----MKFVFTEEEKLL 481

  Fly   610 SEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLH-QKYLEIGMKPRIKNHF 673
            |..::.:|.||||.||||     ...||.           |...|  | ::||::.::|.:....
  Rat   482 SRKMIKYWANFARHGNPN-----SEGLPY-----------WPALD--HDEQYLQLDIQPVVGRAL 528

  Fly   674 RAHQLSIWLRLIPE--LHRAGMEDVIARHNLFRNHDDM 709
            :|.:|..|.:.:|:  ....|.:|         ||.::
  Rat   529 KARRLKFWTKTLPQKIQELKGSQD---------NHTEL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	169/656 (26%)
Ces2e	NP_001093947.1	COesterase	30..536	CDD:278561	169/656 (26%)
		Aes	<127..>230	CDD:223730	50/107 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810