Protein Alignment Nlg4 and cest-31

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 165/609 - (27%)
• Similarity: 238/609 - (39%)
• Gaps: 171/609 - (28%)

  Fly    67 VEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEY 131
            |..:||:|||.||....||....:...|...|...||.|.||                |.|.| |
 Worm    36 VHGYLGIPYAQPPIGILRFKKPVSADVWTETRDCTKYGPRCP----------------PSGML-Y 83

  Fly   132 LKRLLPFLENQSE-DCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPY-DGSVLAS--YG 192
            ....||..:...| :||.||||.|........|.||::||||..||.|:...| |.|:..:  ..
 Worm    84 ENLQLPNTDIPDEANCLSLNVFCPQWEIKQSAKHPVMIFIHGGGFELSASKDYCDYSLSGTLPLK 148

  Fly   193 EVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGT 257
            :|:|||:|||:|.||||....:    :...|:||.|...||.|:..:|..|||||.:|||.|...
 Worm   149 DVIVVTVNYRVGALGFLTTGDD----SCRGNFGLWDLTLALKWVSTHISSFGGDPKNVTLFGQSA 209

  Fly   258 GAACINYLMTSPTMVRGLFHRAILMSGSAYSSWAL--VEDPVLFAIKLAKEVNCTIPDDINRHHE 320
            ||.|.:.|..|| ..|.|||:.|:|||||:..:|:  .|:..|..::.|:....:     .....
 Worm   210 GAVCADLLNLSP-YSRDLFHKLIIMSGSAHVPFAIRTEENQALVCMEYARSRGFS-----GSGSA 268

  Fly   321 QIVDCLRDVPLEDL-------YLADIQAPNFLTSFGPSVDGVVI-RPGHSNLDIDDLMARNSRRS 377
            ::::...::|:|.|       :...|.     .||.|::||... :|      :::| .|.:|:.
 Worm   269 ELLEFFENLPIEKLLEKTGLKHTVSID-----LSFAPNLDGDFFPKP------LEEL-RRETRKK 321

  Fly   378 SADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWR 442
            ....|.....                |..::|..|.|                    .|.|
 Worm   322 PVIVGMMEDE----------------GLITAFADGDF--------------------TTCE---- 346

  Fly   443 FSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDW-DRTSQHPINTRDTAVAALS 506
               .:.:...|.|.|..:    |.|..|...|     |:|.||:: |.:.:..:
 Worm   347 ---ENFKRRVESEYRGDV----VENPENVQKN-----IMNFYTNYCDESEERKL----------- 388

  Fly   507 DAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRC-YFYVFDYQTKDGD 570
             ..::                        |....||....||.|...:|.| ||||||:...||.
 Worm   389 -VDYI------------------------GHSVYNAGVLLSAESLARAGNCVYFYVFDFWNPDGF 428

  Fly   571 YP-----QRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHH 630
            .|     ...|..|..:|.||.|..:   :|.|..|  :.:..:.|.:...:||||:.||||
 Worm   429 GPVGSIVPFKGAAHCSELRYIIGEGV---YSKFDAN--EKDLKMMEYMTTMFTNFAKYGNPN--- 485

  Fly   631 RQDSSLPVSKERNRFRSIT-WENY 653
                 :|         .:| ||.|
 Worm   486 -----IP---------GVTNWETY 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	165/609 (27%)
cest-31	NP_504692.3	COesterase	16..522	CDD:395084	165/609 (27%)