Protein Alignment Nlg4 and cest-30

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 644
• Identity: 163/644 - (25%)
• Similarity: 242/644 - (37%)
• Gaps: 183/644 - (28%)

  Fly    67 VEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEY 131
            |:.:||:|:|..|....:|....|...|...|...:|.|.|||                .||...
 Worm    55 VDGYLGIPFAKAPVGALKFKKPVAAEKWTEPRDCYEYGPGCPQ----------------TGRFAA 103

  Fly   132 L--KRLLPFLENQSEDCLYLNVFSP-VNAGANEKKLPVIVFIHGESFE---WSSGNPYDGSVLAS 190
            |  |....|.|   |:||.||||:| .......|.|||:|:|:|..:|   .|..:.|..:....
 Worm   104 LTAKSTAAFAE---ENCLTLNVFAPRWKLAEFPKGLPVLVYIYGGGYEIGFTSYMDDYSLTGTLP 165

  Fly   191 YGEVVVVTLNYRLGILGFLN-----ANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSV 250
            ..:|:|||:|||||.||||.     ||         .||||.||..||.|:|.||..|||:|.||
 Worm   166 LKDVIVVTMNYRLGPLGFLTIADGIAN---------GNYGLWDQTLALQWVQDNIASFGGNPESV 221

  Fly   251 TLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDI 315
            ||:|...||...::|..||.. ..||.|:|.|||:|:.:         |||:         |.|:
 Worm   222 TLSGTSAGATSTDFLSLSPHS-NQLFQRSISMSGTAFCN---------FAIR---------PKDV 267

  Fly   316 NRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDL----MARNSRR 376
                 ::..|..        .|..|                   |::..|...|    ||:|..:
 Worm   268 -----EVGVCKE--------FAQFQ-------------------GYTGTDSQSLFDWYMAQNVSK 300

  Fly   377 SSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIW 441
            ....:||||:|            .|......:|.|.:|..............|.|..|||.||:.
 Worm   301 FKEVAGFQSTA------------AGAVPFIPNFDGDFFPKPFDILRREAPKKDALITVVTMESVG 353

  Fly   442 RFSAHDI----QNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYT-----DWDRTSQHPINT 497
            ....:.:    .|.|||         ::...|...:.:.:..:..:.|     |.:.:.:..:|.
 Worm   354 MIIFNPLFANAYNNFEG---------FINETYGPDVTDYYADVKKKLTGFYLKDVNASDKATVNR 409

  Fly   498 RDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVF 562
            |  .|..:||:.|     .:|.:.|..|.....:....||                     |..|
 Worm   410 R--VVDYVSDSVF-----NSGTLDAVKSYVKYGNKVYLGS---------------------FNYF 446

  Fly   563 DYQTKDG---DYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTG 624
            :..|||.   ..|.:..: |..|..|.||:.::..|:.     |..|..:.:.......||.:.|
 Worm   447 NDATKDMVELMQPFKEAS-HSSDFKYYFGSGVMANFTP-----TDEEMEVMDMSGTLMANFVKYG 505

  Fly   625 N-----------------PNEHHRQDSSLPVSKERNRFRSITWENYDPLH---QKYLEI 663
            :                 ||.:::.|  .|..:..:.|::.....||.::   :||.:|
 Worm   506 DPNGKSGTKPWKPYTILKPNMYYKID--YPTCEMSDNFQNGRLRIYDDINKNSKKYQQI 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	163/644 (25%)
cest-30	NP_504407.1	COesterase	31..539	CDD:278561	157/619 (25%)
		Aes	<122..>230	CDD:223730	49/116 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900