Protein Alignment Nlg4 and cest-16

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 700
• Identity: 185/700 - (26%)
• Similarity: 265/700 - (37%)
• Gaps: 211/700 - (30%)

  Fly    12 LLLLPTVLISWMHCAGASTADIYKGARL-GHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPY 75
            ||||.|.:.||.:           |..| ..|.|....|.:.|.|..:|.    :.:::|.||||
 Worm     4 LLLLLTFIFSWAN-----------GQLLEKSRSVWVEQGLVRGNIYNIDG----KHIQIFRGVPY 53

  Fly    76 ATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLE 140
            |.||..:.||.|......|.....:.:|.|.|.|.:...:|:..|...|               :
 Worm    54 AEPPIGELRFKPPVKKTRWHQELPAVEYGPPCLQFMDFHKNDKFAKTNM---------------D 103

  Fly   141 NQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESF-EWSSGNPYDGSVLA----SYGEVVVVTLN 200
            .|||||||||||||.:.....|..|::|:|||.|| ..|:....|..|:|    |.| :..|::|
 Worm   104 RQSEDCLYLNVFSPYDTDDESKTYPILVWIHGGSFLAGSADTGIDMEVIAANIVSKG-IAFVSIN 167

  Fly   201 YRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYL 265
            ||||.|||:|..   :......|:|:.|.:.||.|||.||::|.|||..||:.|...|.|..:.|
 Worm   168 YRLGPLGFMNYQ---NGDKLEGNFGIWDMVMALQWIQSNIKQFNGDPTKVTVMGESAGGAASSLL 229

  Fly   266 MTSPTMVRGLFHRAILMSGSAYSSWAL---------VEDPVLF---------------------- 299
            ..|| ...||.|:||:||||:.:.||:         |::.|.:
 Worm   230 ALSP-KTSGLLHQAIIMSGSSMAGWAIHRHSQPAYSVDNLVAYFRCEKWINEDDTKEVVGDEYQH 293

  Fly   300 ----AIKLA------KEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDG 354
                .|:.|      .::|| :.||:.:..:  ::|||    ::|   :..:|.|..:....:
 Worm   294 LTHSVIRSALCNYQNVKINC-LTDDMTQMDK--MNCLR----KEL---NFSSPLFRKALAAEL-- 346

  Fly   355 VVIRPGHSNLDID-DL-------MARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGG 411
                 |.|.:.:| ||       :.||:.|....:|.....
 Worm   347 -----GVSKMVVDGDLVPSSGVSLVRNNARIPIMTGVARKE------------------------ 382

  Fly   412 GYFGGSGAGTMNMGGHY-DVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNE 475
              :|...|...||  |. |.|......|.::|.    |.|.|.....:|:..:.|:...|..:..
 Worm   383 --WGHKKAMFYNM--HQRDGLKRSDVEEQVYRI----IDNSFHETASEKLANSTVQLIANATIVR 439

  Fly   476 IFYTIVNEYTDWDRTSQHPINTRDTAVAAL----SDAQFVAPIVRAGDILAANSPPPVSSSSTAG 536
            ...|..||:            ..|..|.||    ||.:||||..|           .|::....|
 Worm   440 YLETPNNEF------------IADQVVGALQKLESDIEFVAPCER-----------EVAAYVDKG 481

  Fly   537 SPGANAAASTSAGSTQPSGRCYFYVFDYQTKD-------------GDYPQRM-----------GT 577
            .|                  .|.|.|||..|.             |..|..|           ..
 Worm   482 VP------------------VYLYSFDYVPKSPILESERKIYSLFGTKPVEMKRTEKSEILEKAA 528

  Fly   578 VHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPN 627
            .||.|..:||.......|...|  |||.|..:|:.:....|||.:.|:|:
 Worm   529 FHGLDHAFIFSKGYSSNFEISP--YTKREETMSKILCTMLTNFVKNGDPS 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	175/667 (26%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	175/667 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910