Protein Alignment Nlg4 and glit-1

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 696
• Identity: 180/696 - (25%)
• Similarity: 274/696 - (39%)
• Gaps: 189/696 - (27%)

  Fly    56 LPLDSFRF----LR-----SVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIR--ISDKYSPVCPQ 109
            ||.|...|    |:     :|..|||||||.|||.|.||.|.:....:.|.:  ::..|:..|.|
 Worm    86 LPKDGTHFDPNPLKPKNNITVFTFLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQ 150

  Fly   110 RLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGES 174
                      .:||.|.   .::....||:.:  |||||||:|||..:...:...|||||.||.:
 Worm   151 ----------DVEKSPS---PFVDHPYPFMVD--EDCLYLNIFSPDISKNAQTTYPVIVFFHGGN 200

  Fly   175 FEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQN 239
            |:..|.|.:....|||.| :||||:|||||..||::.     ..:...||||.||..||.:::.|
 Worm   201 FQTGSANEWPAHGLASRG-MVVVTVNYRLGAFGFMSM-----GDSETGNYGLQDQRLALEFVKNN 259

  Fly   240 IQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLF---AI 301
            |..|||||.:||:.||..|||.|.:.|.|| ..|.||..|..|||:..|..:.:....|.   .:
 Worm   260 IVTFGGDPQAVTVVGHDAGAASIGFHMQSP-YSRHLFRSAATMSGAEVSYHSYIGKTALAFNNTM 323

  Fly   302 KLAKEVNCTIPDDINRHH---------EQIVDCLRDVPLE-DLYLADIQAPNFLTSFGPSVDGVV 356
            ||.:...||  ..:.:|.         ..|:|..|::|:| :.||           |.|:|||..
 Worm   324 KLGRYAGCT--QAVAQHRWDCILTRSTGDIIDATRNIPIEYNRYL-----------FMPTVDGKY 375

  Fly   357 IRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGT 421
            : ||:   .:..|:...|..:|..|......|
 Worm   376 L-PGN---PLWTLVNAPSGETSIMSPVPMLIG--------------------------------- 403

  Fly   422 MNMGGHYDVLFGVVTGESIWRFSA-HDIQNGFEGERRDKIIRTY-----VRNAYNYHLNEIFYTI 480
            ||.....:|   |:....:..||. :|:.:.:        :::|     .|:.|:.:.......|
 Worm   404 MNAQDGSEV---VLEDRRLGEFSQFNDVDHEY--------LKSYSLEYCYRHNYSMNREATADAI 457

  Fly   481 VNEYTDW-DRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAA 544
            :::||.| ||.:...|  ::..:...:||.:.||:..:..:
 Worm   458 LSKYTFWPDRAAAWAI--KENFIQFATDAYYTAPMQLSSHL------------------------ 496

  Fly   545 STSAGSTQPSGRCYFYVFDYQTKDGD-----YPQRMGTVHGEDLPYIFGAPLVDGFSHFPQ---- 600
            .:|:||     |.:.||.:|......     .|..||.....||..:||.|.:      |.
 Worm   497 HSSSGS-----RVFQYVNNYNFSRQHPNLLFIPDWMGVCRDCDLYLMFGYPFL------PDELRP 550

  Fly   601 ------NYTKSETALSEAVMIFWTNFARTGNPN-------------EH--------HRQDSSLPV 638
                  |:|.::...|.........|:...|||             .|        |.:|..:|.
 Worm   551 IGLRGINFTDTDRNASRTFSNIIRRFSYHQNPNFQFDGSWAAYEPRRHWYINFNYTHEEDWKIPG 615

  Fly   639 SKERN-RFRSIT-WENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWL 682
            :..|: |::.:. |..|.|....|:.....|....:.|...:..|:
 Worm   616 TLARDYRYQDVAFWNEYIPALVNYMTTTFSPENVAYRREIMVFKWI 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	179/693 (26%)
glit-1	NP_508807.1	COesterase	56..629	CDD:365897	173/662 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880