Protein Alignment Nlg4 and cest-5.1

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 701
• Identity: 148/701 - (21%)
• Similarity: 240/701 - (34%)
• Gaps: 234/701 - (33%)

  Fly    10 LRLLLLPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVP 74
            ||||||..::         :.||        ..|:.|.:|.|.|        ..:....:|..:|
 Worm     4 LRLLLLIFII---------NAAD--------SLIIHTSFGHLEG--------AEIGDYHLFKKIP 43

  Fly    75 YATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFL 139
            :|.||....||....|...|||||.:.:|.|.|      :.|.:..  |.|:..::
 Worm    44 FAKPPVGNLRFQKPEAAGKWDGIRSAIEYGPAC------MSNSSKT--KSPQKWVD--------- 91

  Fly   140 ENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLAS---YGEVVVVTLNY 201
                ||||::|:|:.... ...:...:.|:|||....:.|...::.:||..   ..:|::|...:
 Worm    92 ----EDCLHVNIFTSKKC-LKSRNCAIAVYIHGGGLTYDSAVMFNDTVLLDTFVKRDVILVIPGF 151

  Fly   202 RLGILGFL---NANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACIN 263
            ||||....   |.|..|:      |..|.|...||.:::..|..|||:...:||.||..|....:
 Worm   152 RLGIFSHFTVHNQNVAPN------NLALYDITLALEFVKSEIHSFGGNSQKITLFGHSYGGGLAS 210

  Fly   264 YLMTSPTMVR--GLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQ----- 321
            .:..|..:.|  .||.:||:|||..|  :..::|.:....:..:..||::|..:.|..|:
 Worm   211 MMTFSSEINRDLSLFQQAIVMSGGFY--FEELKDHIEGTKRFVEYANCSVPLKLERKMERSQQEM 273

  Fly   322 -IVDCLRDVPLEDLYLADIQAPNFLTSFG-PSVDGVVIR----PGHSNLDIDDLMARNSRRSSAD 380
             ::.||:  .|..:.|..||  ..|...| |...||::|    |     |:.......|.::
 Worm   274 YMMKCLQ--KLSGMELLRIQ--RLLEDKGYPDFGGVILREPLFP-----DVKKFELLKSPKN--- 326

  Fly   381 SGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSA 445
                                                               ..::||.:...|..
 Worm   327 ---------------------------------------------------IPMLTGCTNLEFDH 340

  Fly   446 HDIQNGF----EGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALS 506
            ..|:..|    |.|..|:....|        .|::...:.|.....|:|.
 Worm   341 ESIKVPFGKYLEFENPDECDEKY--------RNDVESGVENRGNHTDKTQ--------------- 382

  Fly   507 DAQFVAPI-VRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGD 570
              ..:.|: ::..::|..|        .||                        |:::|     .
 Worm   383 --GIILPLKLQINNLLENN--------VTA------------------------YLYEY-----T 408

  Fly   571 YPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPN---EHHRQ 632
            ||:. |. |.:||.||.|   |..|.. .:|....|....:.|:    ||.:.|.|.   |...|
 Worm   409 YPKH-GR-HTDDLSYIMG---VHAFEK-DENEVHLEQVYKDMVI----NFIKLGEPGMGFEKSEQ 463

  Fly   633 DSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLR 683
            :.|        .:..|.|..         ..|.:||::.:|.......||:
 Worm   464 NES--------TYFDIYWNE---------TTGERPRMRKYFEKEVTDYWLK 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	138/664 (21%)
cest-5.1	NP_501022.3	Abhydrolase	19..495	CDD:389770	138/665 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900