Protein Alignment Nlg4 and LOC1280747

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_061513099.1
• Gene: LOC1280747 / 1280747
• VectorBaseID: AGAMI1_007562
• Length: 1118
• Species: Anopheles gambiae
• Alignment Length: 1310
• Identity: 428/1310 - (32%)
• Similarity: 605/1310 - (46%)
• Gaps: 315/1310 - (24%)

  Fly     9 LLRLLLLPT-----VLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVE 68
            :|:..|:|.     :.:.|..|:.| .|....|.|...|||.|:.|.:.|:||.|:| :.|..||
Mosquito    36 VLQTKLVPARATIWLWVLWCACSFA-VAPARAGPRYSSRIVDTKSGAIRGVILELNS-KHLEPVE 98

  Fly    69 VFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLK 133
            ||..|||||||....||.|.:...||.|.:::|.:..||||..|:|.|.||||..|||||.::||
Mosquito    99 VFKAVPYATPPIGSLRFEPPKKLPPWKGTKLADTFGSVCPQSFPDISNRTAALLSMPKGRYQHLK 163

  Fly   134 RLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVF--IHGESFEWSSGNPYDGSVLASYGEVVV 196
            ||.|.|.|||||||.||::.| .:|:...:.|..:|  ||||:::|.||||||||||||||.|:|
Mosquito   164 RLQPLLANQSEDCLTLNIYVP-GSGSRGLEAPYSIFFYIHGEAYDWGSGNPYDGSVLASYGHVIV 227

  Fly   197 VTLNYRLGILGFL--NANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGA 259
            ||:|:||||||||  .|:.:|.:.   .|.||||.:.||.|::.||..|||||..:|:.||.|||
Mosquito   228 VTVNFRLGILGFLKTRASLSPGSG---GNLGLMDIILALQWVRDNIASFGGDPKRITIVGHDTGA 289

  Fly   260 ACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHH---EQ 321
            |..|..:.|.. .:||..||||:||||.|.|||:.||....:::::::.|.:....|...   :.
Mosquito   290 ALANLALISKA-GKGLVQRAILLSGSALSPWALIPDPDAVRLEVSQQMACHLVPGRNGRKPTTDD 353

  Fly   322 IVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSS 386
            |.:||||.|:|.|....:.:..|:.|:||.            |.::|.|........:..||.:|
Mosquito   354 ITECLRDKPIEALMGVRLTSVRFMPSWGPF------------LPLEDSMDPEFAMEHSGEGFITS 406

  Fly   387 AGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNG 451
                                                      :::.|:.|.||...|||.|||.|
Mosquito   407 ------------------------------------------ELMLGMTTTESYSDFSASDIQYG 429

  Fly   452 FEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVR 516
            .|.::|::::|||:|||:.:||||||..:.|||||||:..|||||.||:.:.||||...||||::
Mosquito   430 LEEDQRNRLLRTYIRNAFTFHLNEIFSAVRNEYTDWDKPIQHPINIRDSTMEALSDGHTVAPIIK 494

  Fly   517 AGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGE 581
            ...:.|..              ||               :.|.:.|.||:|:.:||||:|:|.||
Mosquito   495 VAYLHARR--------------GA---------------KTYMFHFGYQSKESEYPQRLGSVRGE 530

  Fly   582 DLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNE-HHRQDSSL----PVSKE 641
            |||||||.|||.|...|||||::.:..::|||:.|.|||.:||:||| .|:|.:.|    ..:||
Mosquito   531 DLPYIFGLPLVQGGPVFPQNYSRQDMGVNEAVLNFVTNFCKTGDPNEAGHQQAAPLHPDYGTAKE 595

  Fly   642 RNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIPELHRAGMEDVIARHNLFRNH 706
            |.|||.||||.|:...|:||.|..||::::|:|.|::::||.|||:|||.|..:|..||:.||..
Mosquito   596 RTRFRLITWETYETTTQQYLSISTKPKMRSHYRGHKMALWLNLIPQLHRPGDPEVSMRHHHFRER 660

  Fly   707 DDMDLYEGPVKPDPFGISTAAGASGSSSSSSSSSRLLLVDEQLMMKKGRGLNGSAYLNGILGVTT 771
            :. ..|.|.|:.:.|                |..|                  |.|.||::....
Mosquito   661 EP-HYYAGSVRAESF----------------SRPR------------------SLYQNGVINDAQ 690

  Fly   772 VEPNNMY-TTCIP------------IGGNYSSSGGVFAPTTLANASS----DTLASGFEAAGYAA 819
            ......: |.|.|            :||    .||  ...||.|..|    :.|........|.:
Mosquito   691 ESRQESFGTECTPDPTMGEVLQENGVGG----GGG--PGDTLTNVLSEEEEEELLEKLANRHYYS 749

  Fly   820 YSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLEVKTLQKQYQQRSLHQQVPYPPEPIKHAHY 884
            |:.||.||:.:||.||:||:|||||:|||||:|:.:.:|.|....
Mosquito   750 YTAALGVTVGVGCLLLLLNMLIFAGIYYQRDRTKRKSQTSQSSGT-------------------- 794

  Fly   885 HMGHSQSSANVIVDVESHQDQAGQAAM-LLQAAAAAAAAAANDVKPPPPHIC---------SNTG 939
             :|.|..::.....:........::.: |....:.:...|...::|||.:..         ::||
Mosquito   795 -VGGSGVTSGTSASLSGSNGTPDESEIPLTSIPSPSPVKAKRTIEPPPSYATLPKRTGNNGASTG 858

  Fly   940 MQQQ--------QQVGGGSGGALNNGGIEGSKVTTDNL--GNVT---------YSTSSKQQQQHQ 985
            :..|        |.:.|||.|..:..  .||..|:.:|  |..|         |.:|:..:||||
Mosquito   859 IHHQHQHHHHLHQHLAGGSSGTKDTK--LGSPPTSTHLRTGASTLGRSGTGSFYDSSTSSRQQHQ 921

  Fly   986 QQQQQQQREHMQIKGMTGTQTFGRSGSGSGGGAGGGAGSASGGASVVVSGSSVSYNPGMMTLPKS 1050
            ||||....:          |......:..|..|          .::..:.::||::   .|||::
Mosquito   922 QQQQPYLTQ----------QVIAPHSTNVGHTA----------VTITPAAATVSHH---QTLPRA 963

  Fly  1051 GGLHHAATLNYARNTTALNMSGGGTALVDSRGNVLLTSTAVGPGMAGTGAGGGSSGGGGGGDCMT 1115
            .    .|.|...|:||..:.|...::...|...|.|||..|......|...
Mosquito   964 S----KAPLPPIRSTTCSSSSASSSSGTASTSVVPLTSILVNSNSTTTNNN-------------- 1010

  Fly  1116 LPRNLGLAAAGRHNPTTELQQYQQQQQSSKHQSNGAVLTGMQSHHIRGPRPPLRTASSTTTN-SS 1179
                      ..|.|    ..||||   |...:|..:             ||...:|..|.: .|
Mosquito  1011 ----------NNHQP----HHYQQQ---SCEMANATL-------------PPQPNSSVITVDLVS 1045

  Fly  1180 SNNSAMGVAVGVGGGVGNMLLDQTPSGGSSSSGVSSAPSSSKGHHTHSHSHAAHLVHSH--GDGL 1242
            |...|...|.|                        |:|.:..|.|.|.|.|..|..|.|  |.|.
Mosquito  1046 SATVAAAAATG------------------------SSPPTVLGQHQHQHHHHHHHAHHHASGSGS 1086

  Fly  1243 VLTSASPVGG 1252
            |.|.:.|.||
Mosquito  1087 VTTGSGPAGG 1096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	271/649 (42%)
LOC1280747	XP_061513099.1	None