Protein Alignment Nlg4 and LOC1277285

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_316734.5
• Gene: LOC1277285 / 1277285
• VectorBaseID: AGAMI1_010201
• Length: 598
• Species: Anopheles gambiae
• Alignment Length: 691
• Identity: 170/691 - (24%)
• Similarity: 257/691 - (37%)
• Gaps: 229/691 - (33%)

  Fly    19 LISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQN 83
            |:.|.:.:..|.|:  |...:....||.:.|.::|:   .|.....:|...|.|||||..|....
Mosquito     8 LMGWKNVSTGSDAE--KHMPITRICVQVQQGSVYGV---RDKLPNGQSYYYFKGVPYAKAPVGAL 67

  Fly    84 RFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLY 148
            ||   ::|||.:...:|  |.. |.:...|...            |:.|.:.:    :.|||.|:
Mosquito    68 RF---KSPAPLEKFAVS--YLD-CTRERSNCLG------------LDVLTKEI----SGSEDGLF 110

  Fly   149 LNVFSP-VNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGE-------------VVVVTL 199
            ||:::| :....:.:.|||:|||||            |.::..:|:             |:||||
Mosquito   111 LNIYTPKLGKRDDSEPLPVMVFIHG------------GGLIGGHGDSSLYLPNYLVQEGVIVVTL 163

  Fly   200 NYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINY 264
            |||||:||||..   |.|... .|.||.||.|||.||.:||..||||.::|||.|..:||..:|:
Mosquito   164 NYRLGVLGFLCL---PDAGIE-GNAGLKDQRAALRWISENIGVFGGDASNVTLFGASSGAIAVNF 224

  Fly   265 LMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDV 329
            ...||...| .||:|||.|||.|:.:|..|.|...|.:|||.:..:...|     .::.:.||..
Mosquito   225 HCLSPESKR-YFHKAILQSGSIYTEFAFQEQPEEKARRLAKLLGHSPATD-----GEVYEILRAA 283

  Fly   330 PLEDLYLADIQAPNFLTS------------FGP------SVDGVVIRPGH--------SNLDIDD 368
            |...|:  ::| |..||.            |.|      |.|.::.|  |        :::||..
Mosquito   284 PARKLF--ELQ-PLVLTEREKAVERLFQIPFLPVIERSDSPDALITR--HPTEILSEPNSMDIPI 343

  Fly   369 LMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFG 433
            ::..|.|                                           .|.|
Mosquito   344 ILGYNER-------------------------------------------DGMM----------- 354

  Fly   434 VVTGESIWRFSAHDIQNGFEGERRDKIIRTYV-------RNAYNYHLNEIFY-------TIVNEY 484
             |..::|...:|::.    |.||  .|.||..       ..|....:.|.::       ..:|:.
Mosquito   355 -VLIDTIKTLAAYNA----EPER--FIPRTVALDYFSPEARALGEEIREFYFGARPVCRDTLNQL 412

  Fly   485 TDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAG 549
            ||        :.|....:|.....:..|...|......
Mosquito   413 TD--------VFTDKYLLAYRMTVELWARHQRRSKFFG--------------------------- 442

  Fly   550 STQPSGRCYFYVFDYQTKDGDYPQRMGTVHG----EDLPYIFGAPLVDGFSHFPQNYTKSETALS 610
                    |.:.||.....|.....:||:.|    :::.|:|.:||:.  :..|:  |.....|.
Mosquito   443 --------YRFAFDGLLNKGKAIMSLGTMKGAAHIDEVYYLFSSPLLR--TEVPE--TDRAYGLR 495

  Fly   611 EAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWE 651
            :.::..|:||||.|.|.      .:.||......||   ||
Mosquito   496 KTMVRLWSNFARYGEPT------PAQPVPDPVVPFR---WE 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	165/667 (25%)
LOC1277285	XP_316734.5	None