Protein Alignment Nlg4 and LOC1273105

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_312052.3
• Gene: LOC1273105 / 1273105
• VectorBaseID: AGAMI1_000342
• Length: 554
• Species: Anopheles gambiae
• Alignment Length: 720
• Identity: 191/720 - (26%)
• Similarity: 263/720 - (36%)
• Gaps: 211/720 - (29%)

  Fly    22 WMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFS 86
            |:.....::|   :|......|:.|..|::.|.......|....|   |.|:|||.||....||:
Mosquito     8 WLLLLALASA---RGQSADRPIIGTSSGQVQGTTEDCGLFCTYYS---FKGIPYAEPPVGALRFA 66

  Fly    87 PTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNV 151
            .....|.|.|:|.:.::...||  .|:.                        |..::||||||||
Mosquito    67 DPVPRAAWTGVRDASQHGSSCP--TPDA------------------------LPAEAEDCLYLNV 105

  Fly   152 FSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYG-------EVVVVTLNYRLGILGFL 209
            :||...|..    ||:||:||.::...||:.      |.||       .||:||||||||:||||
Mosquito   106 YSPSLVGTR----PVMVFVHGGAYVGGSGDD------ALYGARYFMPENVVIVTLNYRLGVLGFL 160

  Fly   210 NANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRG 274
            ....    .:...|:.:.|.:.||.|:|:||..||||...||:.|...|.|.:::|..||..| |
Mosquito   161 GTGD----RSASGNWAIKDCVEALRWVQRNIGAFGGDAGRVTIFGQSAGGALVHFLTLSPLAV-G 220

  Fly   275 LFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLY---- 335
            ||.|||..||||.:||:|..:|...|.|:|.|:.....|...     :|..||.||..||.
Mosquito   221 LFERAITHSGSAINSWSLQPNPRQQAEKIAAELGIHTTDTAT-----LVSALRQVPYRDLISPDQ 280

  Fly   336 --LADIQAPNFLTSFGPSVDGVVIRPGHSNLD---IDDLMARNSRRSSADSGFQSSAGGGGGQGG 395
              |.::..|   .:|||.|: ....||...||   |:.:.:.:.|.....:||...
Mosquito   281 TTLDELMVP---LAFGPVVE-PADTPGQVALDRLPIELIESGSYRAVPLMAGFTDM--------- 332

  Fly   396 GAGGGGGGGSGSSFGG-------GYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFE 453
                     ....|..       |.|     .|.|...|..|.|       :|...|
Mosquito   333 ---------DALLFSAVEMVTNPGIF-----DTFNNNPHLLVPF-------VWNIPA-------- 368

  Fly   454 GERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAG 518
            |......:....|..|                 |......|......:| .|:|.||..|.:..
Mosquito   369 GSAASSAVSQAFRQYY-----------------WQSQPLSPALLAQFSV-YLTDLQFAYPQLEM- 414

  Fly   519 DILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGD-----------YP 572
                                 |...||.|:        .|.|.|.|   |||           .|
Mosquito   415 ---------------------AKRHASRSS--------VYLYQFKY---DGDLNLVKQFAGIPLP 447

  Fly   573 QRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLP 637
               |.:||:||.|:|......| ...|  .|.....:.:.::..||||||.|||..  ..|:.|
Mosquito   448 ---GAIHGDDLCYLFETKQFGG-GELP--ITSHAATVRQRMLRLWTNFARDGNPTP--TADALL- 503

  Fly   638 VSKERNRFRSITWENYDP-LHQKYLEIGMKPRIKNHFRAHQLSIWLRLIPELHRAGMEDVIARH- 700
                    :...|....| :....|.||....::.:..|.:.|.||            |:..|:
Mosquito   504 --------QGTLWRPLSPGMIDATLNIGHDLTMEVNPIASRYSQWL------------DLAGRYG 548

  Fly   701 -NLFR 704
             |:||
Mosquito   549 NNIFR 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	181/672 (27%)
LOC1273105	XP_312052.3	COesterase	25..540	CDD:395084	181/673 (27%)