Protein Alignment Nlg4 and LOC1272656

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_061511343.1
• Gene: LOC1272656 / 1272656
• VectorBaseID: AGAMI1_003866
• Length: 745
• Species: Anopheles gambiae
• Alignment Length: 798
• Identity: 194/798 - (24%)
• Similarity: 305/798 - (38%)
• Gaps: 203/798 - (25%)

  Fly    14 LLPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATP 78
            ||..||:.|:...|.|      |:::....:....|.|.||.:..::.|.  .:..:||:|||.|
Mosquito     7 LLNNVLLFWILSIGLS------GSQMQDATIVLSQGTLIGLKVFPETSRI--PIYAYLGIPYAKP 63

  Fly    79 PTKQNRFSPTRAPAP-WDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQ 142
            |..:.||:|. .|:| |:....:..:.|:||| :.|...|...:|...:.|            ..
Mosquito    64 PVNELRFAPP-VPSPGWNRTLYARDFKPICPQ-IENSSYEDLGIENQFRSR------------ET 114

  Fly   143 SEDCLYLNVFSP---VNAGANEKKLPVIVFIHGE--SFEWSSGNPYDGSVLASYGEVVVVTLNYR 202
            ||||||||::.|   :..|.    .||:|.|.||  :|:|:: |...|..||:.| ::|||:.||
Mosquito   115 SEDCLYLNIWIPETSIRYGG----FPVLVMITGEEMAFDWNT-NRASGLDLAADG-IIVVTVQYR 173

  Fly   203 LGILGFLNANPN--PHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHG-TGAACINY 264
            ..:.|:|:....  |      .|.||:||..||.||:.||||||||.|.:||.||| ||...:..
Mosquito   174 SNVFGWLSLGQKYAP------GNLGLLDQQLALVWIKDNIQKFGGDTNRLTLLGHGTTGGPNVMI 232

  Fly   265 LMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDV 329
            .|.|| ..||||.|||:|||:.||.::.|......:.::.|.:.|..  |:.::   ::.||:..
Mosquito   233 HMVSP-QARGLFARAIIMSGTIYSPYSEVNADTKLSQEIIKILACNY--DVGKN---VLKCLQQK 291

  Fly   330 PLEDL---YLADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGG 391
            .:.||   |....:..|:..:.||.:|..:  |......:||...
Mosquito   292 SIHDLLRAYEYIYRNGNYTINLGPIIDHYL--PVEKRYIVDDPQK-------------------- 334

  Fly   392 GQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGER 456
                                 .|........:|    .:|||:.:.|           .||...:
Mosquito   335 ---------------------LFTAKALIMEDM----PILFGITSNE-----------GGFLYSK 363

  Fly   457 RDKIIRTYVRNAYNYHLNEIFYTIVNEY-------------TDW------DRTSQHPINTRDTAV 502
            ..::.|..:.:...|....:...|:..|             ..|      .:|:.|.|:   ..:
Mosquito   364 WIELARQSIDSLKKYINETLLPNIIERYKFQGAGQDQIRETIHWRYFEQIPQTTAHHIH---AII 425

  Fly   503 AALSDAQFVAPIVRA----GDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFD 563
            ..:|:.::..|..:.    |....:|...||   .|.....||....:.|.:...:...|.|:|
Mosquito   426 KIMSETRYEIPFYKTLKALGTKKQSNRQLPV---GTVEDDIANIQRESKAATQHNASYVYAYLF- 486

  Fly   564 YQTKDGDYPQRM----------GTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWT 618
                  .:|..|          |..|..|||::.|..|......  :..:..|..|.:.:...:|
Mosquito   487 ------HHPNSMDMRGRINFFGGASHSSDLPFLMGPSLYREIGR--RRLSMVEDKLCKKMRSLFT 543

  Fly   619 NFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLE-IGMKPRIKNHFRAHQLSIWL 682
            .|.:.|||....:.||..|.|.|                .||:: |..||.
Mosquito   544 EFIKGGNPTPGRQFDSWTPYSVE----------------LKYIKLISAKPE-------------- 578

  Fly   683 RLIPELHRAGMEDVIARHNLFRNHDDMDLYEGPVKPDPFGISTAAGASGSSSSSSSSSRLLLVDE 747
                ..||..       |:...|..:.:|.|  ::.:..|| |......||.::|.:...|..:.
Mosquito   579 ----SFHRND-------HSSLENTFEDNLQE--IEENVIGI-TGLEEPSSSINNSKNPYNLNPNV 629

  Fly   748 QLMMKKGRGLNGSAYLNG 765
            |...:..|....:.||.|
Mosquito   630 QAEQENARTSKNAIYLAG 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	168/683 (25%)
LOC1272656	XP_061511343.1	None