Protein Alignment Nlg4 and LOC1271040

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_061513477.1
• Gene: LOC1271040 / 1271040
• VectorBaseID: AGAMI1_012863
• Length: 591
• Species: Anopheles gambiae
• Alignment Length: 695
• Identity: 177/695 - (25%)
• Similarity: 267/695 - (38%)
• Gaps: 180/695 - (25%)

  Fly    12 LLLLPTVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFL-----------R 65
            |::|...|:..::.||.|                   |:.:..|:.:|....:           |
Mosquito    10 LVVLSVCLVPLLYSAGVS-------------------GQQNSPIVVIDGLGTVQGTRGRTAWTDR 55

  Fly    66 SVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLE 130
            .:..|..:.||..|..|.||.......||.|:..:......|||...|:.....|
Mosquito    56 EIFKFYNIRYAEAPIGQQRFRNPIPVKPWSGVYNAALPGKPCPQIGMNMSTSDLA---------- 110

  Fly   131 YLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVV 195
                        :||||.|:|::. |..||.   ||:|||||.:|...|.:.|:...|.. .::|
Mosquito   111 ------------AEDCLTLSVYTQ-NVTANR---PVMVFIHGGAFVVGSASLYEPDYLLE-KDIV 158

  Fly   196 VVTLNYRLGILGFLNANPNPHAHARV-ANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGA 259
            :|::.||||.||||:...     |.: .|..::|.:.||.|:..||:.||||..|||:.|...|.
Mosquito   159 LVSIQYRLGPLGFLSTGT-----ANIPGNMAMLDMITALEWVSNNIRFFGGDRTSVTVFGESAGG 218

  Fly   260 ACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVD 324
            |.::.|:.|||:...||||||:.|||.:|.||..:.|...|:.:|:.|||      :|..|.:.|
Mosquito   219 AAVSALLYSPTVREDLFHRAIIQSGSIFSPWATCKSPKEGALDIARRVNC------DRPVETMED 277

  Fly   325 CLRDVPLEDLYLADIQAPNFLTSFG----PSVDGVVIRPGHSNLDIDDLMARNSRR--SSADSGF 383
            |||:||.  |.|.:....:..|.|.    |.|.|..|..|.::    ..|.::.:.  .||....
Mosquito   278 CLRNVPA--LRLMEAYEEHRNTQFNITGYPDVSGACIVIGEAS----PFMPKHPKTLPRSAFRNV 336

  Fly   384 QSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRF--SAH 446
            :..||....:            |..|..|.:            .|.:.:...|.:|.|..  ...
Mosquito   337 ELLAGTTAQE------------GLMFWEGVY------------RYGLSYRPETIQSSWDLLQLID 377

  Fly   447 DIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFV 511
            .|...|.....|        .::.:|  ::|.|.:.  |:.||.:...:  ....|....:....
Mosquito   378 TINERFGASSND--------GSHTWH--QLFSTFLT--TEIDRANYTEL--LPGLVDICGNLAIK 428

  Fly   512 APIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDY----------QT 566
            ||:::.....|..:|                            |:.|.|.|||          .|
Mosquito   429 APVLQDVTRFAHANP----------------------------GKVYLYSFDYSGVPSMYNFSST 465

  Fly   567 KDG-DYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHH 630
            .|. .||....:.|.|||.|:|  ||       .|.....:|.:::|::..||:||.:|.|....
Mosquito   466 DDEFKYPYHNNSFHAEDLFYLF--PL-------GQRLNPRDTEIAKAMVDLWTSFAVSGRPAAAA 521

  Fly   631 RQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRA 675
            .:.|..|||.....:..|. |.|:. .|.|.         |.|.|
Mosquito   522 LKQSWNPVSHFNGPYLKIN-EAYEE-RQNYF---------NEFTA 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	171/664 (26%)
LOC1271040	XP_061513477.1	None