Protein Alignment Nlg4 and LOC1270336

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_309021.5
• Gene: LOC1270336 / 1270336
• VectorBaseID: AGAMI1_010914
• Length: 605
• Species: Anopheles gambiae
• Alignment Length: 726
• Identity: 164/726 - (22%)
• Similarity: 251/726 - (34%)
• Gaps: 237/726 - (32%)

  Fly    27 GASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAP 91
            |.|..:....||:..:::|   |.::|   ..|.....:....|.|:|||.||..:.||:   :|
Mosquito    20 GQSAQEYDPSARIMVKVLQ---GSIYG---TKDRLPNGKPYYCFKGIPYAKPPVGKLRFA---SP 75

  Fly    92 APWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPV- 155
            .|.|...:|  |.....:|...:..:....|                 ...|||.|::||::|.
Mosquito    76 EPIDRYPVS--YLDCSRERSSCLGRDVITRE-----------------ITGSEDGLFVNVYTPAL 121

  Fly   156 ---NAGANEKKLPVIVFIHGESFEWSSGNP--YDGSVLASYGEVVVVTLNYRLGILGFLNANPNP 215
               .:.......||:||.||......:|:.  |....|...| |||.|:|||||:||||..   |
Mosquito   122 GREVSSTGTPLAPVMVFFHGGGMTGGNGDSSMYLPDYLVQEG-VVVATVNYRLGVLGFLCL---P 182

  Fly   216 HAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLM-TSPTMVRGLFHRA 279
            .|... .|.||.||..||.||:||:..||||||:|||.|..:|.:  |.|| ....:.:..||:|
Mosquito   183 QAGIE-GNAGLKDQRLALQWIRQNVSTFGGDPNNVTLFGASSGGS--NVLMHCFSDLSQPYFHKA 244

  Fly   280 ILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLY------LAD 338
            |..|.:.::......:|...|..||:........|     |.::..|||||...||      |:|
Mosquito   245 IAQSATIFADLIYQTEPEERARSLARIFGYEGTSD-----EGVLATLRDVPARRLYEAQFLVLSD 304

  Fly   339 --------IQAP-NFLTSFGPSVDGVVIRP-----------------GHSNLD--------IDDL 369
                    .|.| ..:.....|.|.|:::.                 |:::.:        |.:|
Mosquito   305 REREYEQIFQFPFTAVIEREQSTDPVLVKTPMEYLREPNRMRVPVLCGYNDKEGMLELVDMIKNL 369

  Fly   370 MARNSRRS-----SADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYD 429
            ...|:|..     |.|..:.|.|              ....|......|||.:.....|:....|
Mosquito   370 SVYNARPEKFICRSFDVDYFSPA--------------ARALGEEMRRHYFGEASICRANLDRLVD 420

  Fly   430 VLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHP 494
            :|                         .|:.:..|      |.|.::          |   |:|
Mosquito   421 LL-------------------------TDRFVVGY------YVLCKL----------W---SEH- 440

  Fly   495 INTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYF 559
                          |...|:                                           |.
Mosquito   441 --------------QTATPL-------------------------------------------YS 448

  Fly   560 YVFDYQ---TKDGD---YPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETA--LSEAVMIF 616
            |.|.|:   .|..:   :....|..|.:::.|:|.:||:.  :..|    .|:.|  :.:.::..
Mosquito   449 YRFAYEGSLNKGKELLKFQHLPGACHIDEVYYLFSSPLLR--TEIP----PSDPAYRMRQLMVRM 507

  Fly   617 WTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIW 681
            |||||:..||......:..||...|  ..|::...:..|.:.....||.:             :.
Mosquito   508 WTNFAKHSNPTPPTEDEPGLPCQWE--PMRAVPGTDGQPTNYTVFSIGKE-------------LT 557

  Fly   682 LRLIPELHRAG 692
            :..:|||.|.|
Mosquito   558 MSTLPELERMG 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	155/697 (22%)
LOC1270336	XP_309021.5	None