Protein Alignment Nlg4 and Cel

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_034015.1
• Gene: Cel / 12613
• MGIID: 88374
• Length: 599
• Species: Mus musculus
• Alignment Length: 745
• Identity: 202/745 - (27%)
• Similarity: 290/745 - (38%)
• Gaps: 235/745 - (31%)

  Fly    25 CAGASTADIYKGARLGHRIVQTRYGRLHGL-----ILPLDSFRFLRSVEVFLGVPYATPPTKQNR 84
            |..|:.|     |:||  .|.|..|.:.|:     :|..|      ||::|.|:|:||..|.:|
Mouse    14 CLAAACA-----AKLG--AVYTEGGFVEGVNKKLSLLGGD------SVDIFKGIPFATAKTLEN- 64

  Fly    85 FSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYL 149
              |.|.|. |.|...:..:...|.|......|...                       .||||||
Mouse    65 --PQRHPG-WQGTLKATNFKKRCLQATITQDNTYG-----------------------QEDCLYL 103

  Fly   150 NVFSPVNAGANEKKLPVIVFIHGESFEWSSGNP--------YDGSVLASYGEVVVVTLNYRLGIL 206
            |::.|.........|||:|:|:|.:|...||..        |||..:|:.|.|:|||.|||:|.|
Mouse   104 NIWVPQGRKQVSHNLPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPL 168

  Fly   207 GFL---NAN-PNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMT 267
            |||   :|| |        .|:||.||..|:.|:::||..|||||:::|:.|...|||.::....
Mouse   169 GFLSTGDANLP--------GNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTL 225

  Fly   268 SPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLE 332
            || ..:||..|||..||.|.|.||:.::|:.:|..:||:|.|...|.     .::..||:.....
Mouse   226 SP-YNKGLIRRAISQSGMALSPWAIQKNPLFWAKTIAKKVGCPTEDT-----GKMAACLKITDPR 284

  Fly   333 DLYLA--------DIQAPNFLTSFGPSVDGVVIRPGHSNL-----DIDDLMARNSRRSSADSGFQ 384
            .|.||        :....::| :|.|.:||..|.....||     |||.:
Mouse   285 ALTLAYKLPVKKQEYPVVHYL-AFIPVIDGDFIPDDPINLYNNTADIDYI--------------- 333

  Fly   385 SSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGV---------VTGESI 440
                                              ||..||.||......|         ||.|..
Mouse   334 ----------------------------------AGINNMDGHLFATIDVPAVDKTKQTVTEEDF 364

  Fly   441 WRF-SAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTD-WDRTSQHPI--NTRDTA 501
            :|. |.|.:..|.:|.:                      ...:.||: |   :|.|.  |.:.|.
Mouse   365 YRLVSGHTVAKGLKGAQ----------------------ATFDIYTESW---AQDPSQENMKKTV 404

  Fly   502 VAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQT 566
            ||..:|..|:.|.    :|..|.......|:.|                       |.|:|.:.:
Mouse   405 VAFETDVLFLIPT----EIALAQHKAHAKSAKT-----------------------YSYLFSHPS 442

  Fly   567 KDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHR 631
            :...||:.||..|.:||.|:||.|...     |..|...:.|:|:|::.:||||||:|:||   .
Mouse   443 RMPIYPKWMGADHADDLQYVFGKPFAT-----PLGYRPQDRAVSKAMIAYWTNFARSGDPN---M 499

  Fly   632 QDSSLPVSKERNRFRSITWENYDPLHQKYLEIG---MKPRIKNHFRAHQLSIW---LRLIPELHR 690
            .:|.:|..          |..|...:..||:|.   ....:|.|.|...|..|   ..::|.:
Mouse   500 GNSPVPTH----------WYPYTLENGNYLDITKTITSASMKEHLREKFLKFWAVTFEVLPTV-- 552

  Fly   691 AGMEDVIARHNLFRNHDDMDLYEGPVKPDP 720
            .|.:|     .|....||.:     |.|||
Mouse   553 TGDQD-----TLTPPEDDSE-----VAPDP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	185/683 (27%)
Cel	NP_034015.1	COesterase	26..542	CDD:278561	185/682 (27%)
		Aes	<117..>247	CDD:223730	59/138 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..599		9/30 (30%)
		4 X 11 AA tandem repeats, O-glycosylated region	559..588		7/19 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910