Protein Alignment Nlg4 and LOC11175878

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_003436330.2
• Gene: LOC11175878 / 11175878
• VectorBaseID: AGAMI1_013798
• Length: 633
• Species: Anopheles gambiae
• Alignment Length: 735
• Identity: 173/735 - (23%)
• Similarity: 252/735 - (34%)
• Gaps: 223/735 - (30%)

  Fly     9 LLRLLLLP-TVLISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGL---ILPLDSFRFLRSVEV 69
            ||.||..| ..::..:..|.....|.....|:|.|.     .|:.||   ...|.|||
Mosquito    19 LLALLATPGEAIVGGIRSATPPIDDPVVFVRVGGRA-----ARVEGLRNRNTGLYSFR------- 71

  Fly    70 FLGVPYATPPTKQNRFS-PTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLK 133
              |:.||..||.||||: |.......|....|:  .|.|||  |...|
Mosquito    72 --GIHYAESPTGQNRFARPQYRHLSGDVNATSN--GPPCPQ--PEPSN----------------- 113

  Fly   134 RLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVT 198
               |:.....||||.||:|:| ........|||:|:|||..:.:.|.:.|....|.|.| |:.|.
Mosquito   114 ---PYRVIGHEDCLLLNIFTP-QMPDETTGLPVVVWIHGGGYRYGSASQYGAEPLTSNG-VIFVP 173

  Fly   199 LNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACIN 263
            :.||||..|.:.......:    .|..|:|...|:.|::..|..|||||..:.|.|||:||...
Mosquito   174 IQYRLGSFGMIGDGSRDLS----GNLALLDMATAVRWVRDYIAWFGGDPAQIKLVGHGSGATAA- 233

  Fly   264 YLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRD 328
            .::.|.||.|......:.||||:....|...:||....:......|...::     .::|.||||
Mosquito   234 MVLASATMARSSVTGVVAMSGSSLQPNAYEMEPVGAYREATMRHRCAAGNE-----TEVVKCLRD 293

  Fly   329 VPLEDLYLAD--IQAPNFLTSFGPSVDGVVIRPGHSNL--DIDDLMARNSRRSSADSGFQSSAGG 389
            ...|::...|  :||..|...  ..|:||..:.|.:.:  :.||
Mosquito   294 KSTEEIVQMDTELQAERFRGE--KLVNGVTPQAGLNPVVEEKDD--------------------- 335

  Fly   390 GGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEG 454
                |.|..|........|...|.|           ....:|.||...|:.......:||:.|:|
Mosquito   336 ----GRGLLGLLTDKPEVSLQAGDF-----------PKIPLLIGVTKDETANAIDVKEIQSTFKG 385

  Fly   455 --------------------ERRDKIIRT---------YVRNAYNYHLNEIFYTIVNEYTDWDRT 490
                                |::.:.:.|         |:.....:.:.:||..:|.
Mosquito   386 ATNFLKKTSSLVGLEGFLNVEKQVQALDTVGGILQLDKYLEIPAGWDVTQIFSKLVE-------- 442

  Fly   491 SQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSG 555
                         |.:||.|                              |..|..||.:...|.
Mosquito   443 -------------ATTDAVF------------------------------NLPAVVSAQAWSKSS 464

  Fly   556 RCYFYVFDYQ---TKDGDYPQRMGTV--------------HGEDLPYIFGAPLVDGFSHFPQNYT 603
            :.:.|.|:::   ||..|:...:..|              ||::|..:|....|.|      |..
Mosquito   465 KAFIYSFEHRSDSTKGRDFLAGLPIVAKTGTNGADGRLVGHGDELGLLFDTHDVYG------NPI 523

  Fly   604 KSETALS-------EAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYL 661
            .|.|..|       :|...|...||.....:.|  ||         |.|:|.:.:.     ..::
Mosquito   524 ASATVKSAKDLNARKAFASFIAKFAYLNTSSMH--QD---------NVFKSFSSKG-----TPFV 572

  Fly   662 EIGMKPRIKNHFRAHQLSIW 681
            .:|.|..:.|.||..|||||
Mosquito   573 RVGEKIAVDNDFRFCQLSIW 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	161/698 (23%)
LOC11175878	XP_003436330.2	None