Protein Alignment Nlg4 and nlgn2

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_031755501.1
• Gene: nlgn2 / 100329187
• XenbaseID: XB-GENE-6034906
• Length: 810
• Species: Xenopus tropicalis
• Alignment Length: 957
• Identity: 291/957 - (30%)
• Similarity: 418/957 - (43%)
• Gaps: 267/957 - (27%)

  Fly    19 LISWMHCAGASTADIYKGARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQN 83
            ||.|:  ..|..|:..||.. .:.:|.|.||:|.|:...|:: ..|..|..:||:||||||..:.
 Frog     9 LILWL--LAACPAEGQKGDD-KYPVVNTNYGKLRGVKKDLNN-EILGPVVQYLGIPYATPPIGER 69

  Fly    84 RFSPTRAPAPWDGIRISDKYSPVCPQR----LPNIQNETAALEKMPKGRLEYLKRLLPFLENQSE 144
            ||....|||.|..:|.:..::|||||.    ||.|.        :|....|.:..:..:::||||
 Frog    70 RFQAPEAPASWTEVRNATTFAPVCPQNLHGMLPGIM--------LPLWFTENMDVVAGYVQNQSE 126

  Fly   145 DCLYLNVFSPVNAGANEK--------------------KLPVIVFIHGESFEWSSGNPYDGSVLA 189
            ||||||::.|:..|...|                    |.||::||||.|:...:||.:||||||
 Frog   127 DCLYLNIYVPLEDGPISKSREDPRKAQHTPDEDIRDSGKKPVMMFIHGGSYMEGTGNMFDGSVLA 191

  Fly   190 SYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAG 254
            :||.|:|||||||||||||::...    .|...||||:||:.||.|:::||..|||||..:|:.|
 Frog   192 AYGNVIVVTLNYRLGILGFMSTGD----QAAKGNYGLLDQIQALRWLEENIGHFGGDPERITIFG 252

  Fly   255 HGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHH 319
            .|.||:|::.|:.|... .|||.:||..||:|.|||::..:|:.:...||.:|.|    |...:.
 Frog   253 SGAGASCVSLLILSHHS-EGLFQKAIAQSGTAISSWSVNYEPLKYTRLLAAKVGC----DYQENS 312

  Fly   320 EQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQ 384
            |.:: |||..|..||...|||...:..:|||.|||.|:..     |.:.||.:
 Frog   313 EMVM-CLRRKPYRDLVDQDIQPARYHIAFGPVVDGDVVPD-----DPEILMEQ------------ 359

  Fly   385 SSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRF--SAHD 447
                                       |.|       :|    ||:|.||..||.: :|  ...:
 Frog   360 ---------------------------GEF-------LN----YDILMGVNQGEGL-KFVEDTLE 385

  Fly   448 IQNGFEGERRDKIIRTYVRNAYNYH-----LNEIFYTIVNEYTDW-DRTSQHPINTRDTAVAALS 506
            .::|......|..:..:|.|.|.:.     |.|   ||...|||| ||.:..  ..|.|.:|..:
 Frog   386 SEDGISNSYFDFTVSNFVDNLYGFAEGKDVLRE---TIKFMYTDWADRDNGD--MRRKTLLALFT 445

  Fly   507 DAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDY 571
            |.|:|||.:......|....|                             .|||.|.::.:....
 Frog   446 DHQWVAPAIATAKFHAEYESP-----------------------------VYFYAFYHRCQAEGR 481

  Fly   572 PQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSL 636
            |:.....||:::||:||.|:|.....||.|::|::..||..||.:|||||:||:||:...||:..
 Frog   482 PEWGEAAHGDEVPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKF 546

  Fly   637 PVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIPELHRAGMEDVIARHN 701
             :..:.|||..:.|..::|..::||.||:|||:|:::||::::.||.|:|.||.
 Frog   547 -IHTKPNRFEEVVWTKFNPKEKQYLHIGLKPRVKDNYRANKVAFWLELVPHLHE----------- 599

  Fly   702 LFRNHDDMDLYEGPVKPDPFGISTAAGASGSSSSSSSSSRLLLVDEQLMMKKGRGLNGSAYLNGI 766
                                                                         ||..
 Frog   600 -------------------------------------------------------------LNTG 603

  Fly   767 LGVTTVEPNNMYTTCIPIGGNYSSSGG--------VFAPTTLANASSDTLASGFEAAGYAA-YST 822
            |..:|       ||..|.||...:|.|        .|.|........|.........|.:. |||
 Frog   604 LHTST-------TTRQPTGGTRRTSSGSTTRRPPVTFPPDIDIEEEMDNRPRYSPFPGDSRDYST 661

  Fly   823 ALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLEVKTLQKQYQQRSLHQQVPYPPEPIKHAHYHMG 887
            .||||:|:|.|||.||:|.||.:||:||: |.|::      |:|
 Frog   662 ELSVTVAVGASLLFLNILAFAALYYKRDR-RHELR------QRR--------------------- 698

  Fly   888 HSQSSANVI-VDVESHQDQAGQAAMLLQAAAAAAAAAANDVKPPPPH 933
            ||.....|. .|:..|..:  :..|.||...|..|.   |::|..||
 Frog   699 HSPGRGGVPGNDLAHHGPE--EELMSLQIKRAGGAP---DLEPLRPH 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	224/669 (33%)
nlgn2	XP_031755501.1	COesterase	29..590	CDD:395084	224/670 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	433	1.000	Inparanoid score	I1667
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	1	1.000	-	-		FOG0000662
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X375
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060