Protein Alignment Nlg4 and nlgn4xb

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001159809.1
• Gene: nlgn4xb / 100147967
• ZFINID: ZDB-GENE-100309-1
• Length: 795
• Species: Danio rerio
• Alignment Length: 839
• Identity: 277/839 - (33%)
• Similarity: 389/839 - (46%)
• Gaps: 208/839 - (24%)

  Fly    44 VQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCP 108
            |.|.||:|.||.:.|.| ..|..||.|||||||..||.:.||.....|..|.|||.:.:::||||
Zfish    25 VTTNYGKLRGLRVALPS-EILGPVEQFLGVPYAMAPTGERRFQAPEPPLSWPGIRNATQFAPVCP 88

  Fly   109 QRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPV------NAGANEKKLPVI 167
            |.|   ::.....:.:|......|..:..::.:|||||||||::.|.      :||..    ||:
Zfish    89 QFL---EDRLLLTDMLPVWFTANLDTVATYVHDQSEDCLYLNIYVPTEEETQDDAGLK----PVM 146

  Fly   168 VFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAA 232
            |:|||.|:...:||..|||||||||.|:|||:|||||:||||:...    .|...||||:||:.|
Zfish   147 VYIHGGSYVEGTGNMIDGSVLASYGNVIVVTVNYRLGVLGFLSTGD----QAAKGNYGLLDQIQA 207

  Fly   233 LHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPV 297
            |.|:::|||.|.|||..||:.|.|.||:|:: |:|.......||.:||:.||:|.||||:...|.
Zfish   208 LRWVKENIQSFSGDPERVTIFGSGAGASCVS-LLTLSHYSEDLFQKAIIHSGTALSSWAVNYQPA 271

  Fly   298 LFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHS 362
            .:...||::|.|...|.:     ::::||:....::|...:|....:..:|||.:||.||.
Zfish   272 KYTRLLAEKVGCNEDDTL-----ELIECLQSKNYKELIEQNITPAKYHIAFGPVIDGDVIP---- 327

  Fly   363 NLDIDD---LMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNM 424
                ||   ||.:                                       |.|       :|
Zfish   328 ----DDPQILMEQ---------------------------------------GEF-------LN- 341

  Fly   425 GGHYDVLFGVVTGESIWRF-----SAHD--IQNGFEGERRDKIIRTYVRNAYNY-----HLNEIF 477
               ||::.||..||. ::|     .:.|  ..|.||     ..|..:|.:.|.|     .|.|
Zfish   342 ---YDIMLGVNQGEG-YKFVDGILDSEDRVTSNDFE-----FAISEFVDHLYGYPEGKDTLRE-- 395

  Fly   478 YTIVNEYTDW-DRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGAN 541
             ||...|||| ||  ::|...|.|.||..:|.|:|||.|...|:.|           ..|||
Zfish   396 -TIKFMYTDWADR--ENPEMRRKTLVALFTDHQWVAPAVATADLHA-----------QYGSP--- 443

  Fly   542 AAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSE 606
                           .|||.|.:..:....|....:.||::|||:||.|::.....|..|::|::
Zfish   444 ---------------TYFYAFYHHCQSDMKPAWADSSHGDELPYVFGIPMIGPTDLFNCNFSKND 493

  Fly   607 TALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKN 671
            ..||..||.:|||||:||:||:...||:.. :..:.|||..:.|..|:|..|.||.||:|||:::
Zfish   494 IMLSAVVMTYWTNFAKTGDPNQPVPQDTKF-IHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRD 557

  Fly   672 HFRAHQLSIWLRLIPELHRAGMEDVIARHNLFRNHDDMDLYEGPVKPDPFGISTAAGASGSSSSS 736
            |:||.:::.||.|:|.||..        :.||:                :..||.......::..
Zfish   558 HYRATKIAFWLELVPHLHNI--------NELFQ----------------YVSSTTKIPPQDTTPF 598

  Fly   737 SSSSRLLLVDEQLMMKKGRGLNGSAYLNGILGVTTVEPNNMYTTCIPIGGNYSSSGGVFAPTTLA 801
            |.:.||                    .|.:...||..|.                    ||....
Zfish   599 SYTKRL--------------------SNKLFPSTTRHPP--------------------APPANT 623

  Fly   802 NASSDTLASGFEAAGYAA-----YSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLE 855
            ...||...:...|.|...     |||.||||||:|.|||.||:|.||.:||::||.|||
Zfish   624 KQMSDQQKTSEHADGTVIIEARDYSTELSVTIAVGASLLFLNILAFAALYYKKDKHRLE 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	229/658 (35%)
nlgn4xb	NP_001159809.1	COesterase	24..567	CDD:395084	229/658 (35%)