Protein Alignment Nlg4 and cel.2

DIOPT Version :9

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_001120027.1
• Gene: cel.2 / 100144991
• XenbaseID: XB-GENE-1217488
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 680
• Identity: 180/680 - (26%)
• Similarity: 272/680 - (40%)
• Gaps: 182/680 - (26%)

  Fly    43 IVQTRYGRLH------GLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISD 101
            :|.|..|.:.      |::.|       ..:::|.|:|:|.||   ..|........|.|...:.
 Frog    24 VVHTEGGFVEGTNKKIGVVFP-------DYIDIFKGIPFAAPP---KPFEKAEKHPGWSGTLQAK 78

  Fly   102 KYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPV 166
            .|.|.|.|......|...:|                       |||||||:.|.........|||
 Frog    79 DYKPRCLQATITQDNVFGSL-----------------------DCLYLNVWVPQTRSQVSTNLPV 120

  Fly   167 IVFIHGESFEWSSGNP--------YDGSVLASYGEVVVVTLNYRLGILGFLNANPN--PHAHARV 221
            :|:|.|..|...||..        |||..:|..|:|:|||.|||:|.||||:...:  |
 Frog   121 MVWIFGGGFLLGSGQGANFLSNYLYDGEEVAMRGKVIVVTFNYRVGPLGFLSTGDSNAP------ 179

  Fly   222 ANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSA 286
            .||||.||..|:.|:::||..||||||::||.|...|.|.::....:|..| ||..|||..||..
 Frog   180 GNYGLWDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLTPYNV-GLIKRAISQSGVG 243

  Fly   287 YSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVP------LEDLYLADIQAP--N 343
            ...||:..||:.:|..||.::.|.:     .:.:::.||||:..      ...|.|.:::.|  :
 Frog   244 LCPWAIQRDPLTWAKSLASKLGCPV-----NNTKELADCLRNTDPGALTIAYQLQLFNLEYPLVH 303

  Fly   344 FLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSS 408
            :| ::.|.:||..|.....||                  |.::|
 Frog   304 YL-AYSPVIDGDFIPDEPRNL------------------FSNAA--------------------- 328

  Fly   409 FGGGYFGGSGAGTMNMGGHYDVLFGVV----TGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAY 469
             |..|.    ||..||.||   ||..|    ..:.:.:.|...:|         |::|. :..|.
 Frog   329 -GVDYI----AGVNNMDGH---LFAGVDLPAINQPLHKISTEQVQ---------KVVRG-LTLAK 375

  Fly   470 NYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSST 534
            .....:|.|.:   ||....|:....:.:.|.|...:|..|   :|...:.||.:.
 Frog   376 GVPALDIAYDL---YTAGWGTNPSQEDMKRTVVEVETDYIF---LVATQEALALHY--------- 425

  Fly   535 AGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFP 599
                 .||..:          :.|.|:|.:.::...||..||..|.|||.::||.|    || .|
 Frog   426 -----QNAKGA----------KTYSYMFSHPSRMPVYPSWMGADHAEDLQFMFGKP----FS-TP 470

  Fly   600 QNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIG 664
            ..|...:..:::.::.:|||||.||:|:   :.:||:|.          .|..|...:.:||||.
 Frog   471 LAYRPRDRDVAQYMIAYWTNFAATGDPS---KGESSIPT----------PWLAYSTENGQYLEIN 522

  Fly   665 MK---PRIKNHFRAHQLSIWLRLIPELHRA 691
            .|   ..:|...|:..:..|.:....|..|
 Frog   523 HKINYQSMKQSLRSPYVRFWAQTFINLPNA 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	177/668 (26%)
cel.2	NP_001120027.1	COesterase	24..542	CDD:365897	177/668 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100