Protein Alignment CG10887 and LEO1

DIOPT Version :10

• Sequence 1: NP_650866.1
• Gene: CG10887 / 42399
• FlyBaseID: FBgn0038773
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_014766.1
• Gene: LEO1 / 854290
• SGDID: S000005649
• Length: 464
• Species: Saccharomyces cerevisiae
• Alignment Length: 500
• Identity: 114/500 - (22%)
• Similarity: 204/500 - (40%)
• Gaps: 95/500 - (19%)

  Fly   233 EMEQDLLSK-QHSTSTPINKSNTMEKELLPLQCSSFPPTSSEGNILKPRVNPVPLGPSSNTEYES 296
            |..||...| |.|.:..:..::|..:|         ...|.:.|:.:...|       .:|:.|.
Yeast     4 ESPQDQPQKEQISNNVGVTTNSTSNEE---------TSRSQDDNVKEVNGN-------DDTKEEE 52

  Fly   297 NGKNYNIEKRLSQLRYSSDEKESDVLSYASSDSLDLNFDYGDNAKNQNGNGMNGEVNG--DKESQ 359
            ..::..::.....   .:|:.:.|.:..:.::..|.:.|..|..:|.|....:.|..|  |.|:
Yeast    53 QEEDAELDDLFGD---DNDDDDDDDVKKSETEKSDSDSDEDDEGENINHRSRHRESLGLDDDEA- 113

  Fly   360 VLDIEEQ----RKPFEKDVAVKF----QTTIT--TQNCGLLKG--PSQ-------------FLKM 399
                |||    ||.:.:| |..|    :||.|  .:|..|::.  ||:             :.::
Yeast   114 ----EEQAMYTRKFYGED-ANNFSDQDETTHTFKEENVELVRHIIPSKANVNETASHNEIFYARI 173

  Fly   400 PYFIPVESKAYVPETFQDRMTKNDLKDEQSREDFI-NRL--KATVRWRENENKT----KESNAKI 457
            |.|:.::...:.|.:|:.::.:. ..:..||||.: :||  :.|||||.:.:|.    ||||.:|
Yeast   174 PNFLTIDPIPFDPPSFEAKVNER-ASNSASREDQLDDRLIDENTVRWRYSRDKDQHVFKESNTQI 237

  Fly   458 VRWSDGSETFHVGNEVFDMMHHPVT---VNQNHLYVRLGSFYQPQGLIQNKLTVRPMLDSNFGQS 519
            |:||||:.:..||.|..|::.:..:   :..:|....|...|:...:.:..:.:....:|...|.
Yeast   238 VQWSDGTYSLKVGEECTDILVNDTSNTFLTVSHDQQELIQCYEGGEIKKTLMFIPTSTNSKIHQK 302

  Fly   520 HVQALRNRATNKPQS-GCVKVITNMGSNPEHD------------HDRRMKEELSKLRQEGREK-- 569
            ..:|:..|  |:.|| |....|.:|  :||.:            .|||.::...|.:||..:.
Yeast   303 LSKAVIRR--NQRQSKGPGTYIVSM--DPEVEKKELERKQSQILRDRRRRQLKEKEKQESPDAAF 363

  Fly   570 NRALMKNHPPKRDRHYQGSDHNVAKNAGAFEEDDGEGADCETSSALEVTNEPMRSEEDTEDHMDD 634
            .....|.:.|..   |..|..|      .:||||....|.|...|.....|....||:.|:..|:
Yeast   364 ETGFRKQNSPTT---YGASRRN------EYEEDDFLVDDDEEEEAAFDDEEDDNEEEEEEEDADE 419

  Fly   635 DASWSSPNSQEEGK---QSSSEDDLPIGGAIRKPTRLVYSGSDSD 676
            :.:....|.:.||.   :...|::.......|:...::....|.|
Yeast   420 ENASRLRNLKREGAAMYREEEEEEKDRSETKRRRVAVIEDDEDED 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10887	NP_650866.1	Leo1	396..559	CDD:461126	48/185 (26%)
LEO1	NP_014766.1	Leo1	169..335	CDD:461126	45/170 (26%)