Protein Alignment CG10887 and Leo1

DIOPT Version :10

• Sequence 1: NP_650866.1
• Gene: CG10887 / 42399
• FlyBaseID: FBgn0038773
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001005548.1
• Gene: Leo1 / 300837
• RGDID: 1549772
• Length: 678
• Species: Rattus norvegicus
• Alignment Length: 715
• Identity: 174/715 - (24%)
• Similarity: 288/715 - (40%)
• Gaps: 141/715 - (19%)

  Fly    56 FHSTANSVPESQGPLESRSDLNAKTSSKSERPYISTSNSSWTSESSSGSPPDSGESSS---FSTS 117
            |.|.|.|..|       |.|.::.:.|.|::...::.:::..|||......|||:.|:   |...
  Rat     8 FGSEAESEAE-------RKDSDSGSDSDSDQDNGASGSNASGSESDQDERGDSGQPSNKELFGDD 65

  Fly   118 SSLSSSLLCAPEPKSINWSNPKSSSNISNETTTSAGQVGGIPSFSESDDQGSVDSETVSNIRKST 182
            |....    ||.         .|.|:..:|.:.:..:.....|..|.::...||..:.|.....
  Rat    66 SEEEG----APH---------HSGSDNHSEQSDNRSEASEERSDHEDNEPSDVDQHSGSEAHND- 116

  Fly   183 SLIELKDNFNTIIDEDNNQQLSNEGNILS---------------PGTVSISNFPSSNEVANGLID 232
                 .|:.:...|:|:....|:||:..|               .|...........::.|...:
  Rat   117 -----DDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDE 176

  Fly   233 EMEQ--DLLSKQHSTSTPINKSNTMEKELLPLQCSSFPPTSSE--GNILKPRVNPVPLGPSSNTE 293
            |.||  |....|:|........||.:::...|........|.|  ||....|.     ..|.|.|
  Rat   177 EREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERP-----AASDNDE 236

  Fly   294 YESNG------------KNYNIEKRLSQL-----RYSSDEKESDVLSYAS--SDSLD-------L 332
            .:.|.            |..|.:....|:     |:|.||:|.|..|.::  |||.|       .
  Rat   237 EKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSDSEDEVLRMKRK 301

  Fly   333 NFDYGDN--------AKNQNG------------NGMNGEVNGDKESQVLD---IEEQRKPFEKDV 374
            |....|:        .|:.||            :|.:||.......|.:|   :.:.::..|...
  Rat   302 NAIPSDSEVDSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIP 366

  Fly   375 AVKFQTTITTQNCGLLKGPSQFLKMPYFIPVESKAYVPETFQDRMTKNDLKDEQSREDFINRLKA 439
            ..:.:..|...|.. |.....|:|:|.|:.||.:.:.|:.::|.....::.||:.|.....:::.
  Rat   367 ETRIEVEIPKVNTD-LGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVEN 430

  Fly   440 TVRWR----ENENKTKESNAKIVRWSDGSETFHVGNEVFDMMHHPVTVNQNHLYVRLGSFYQPQG 500
            |:|||    |..|:.|||||:||:|||||.:.|:||||||:...|:..:.|||::|.|:..|.|.
  Rat   431 TIRWRMRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQA 495

  Fly   501 LIQNKLTVRP-MLDSNFGQSHVQALRNRATNKPQSGCVKVITNMGSNPEHDHDRRMKEELSKLRQ 564
            :.:.|||.|| ..||...:....:|.:|. :|.|.  ::::...|.:||......:|:|..:||.
  Rat   496 VFKTKLTFRPHSTDSATHRKMTLSLADRC-SKTQK--IRILPMAGRDPECQRTEMIKKEEERLRA 557

  Fly   565 E-GREKNRALMKNHPPKRDRHYQGSDHNVAKNAGAFEEDDGEGADCETSSALEVTNE---PMRSE 625
            . .||..:..|     :..:|.:|...:..:.....||::||    |:.|...:.|.   .:|.|
  Rat   558 SIRRESQQRRM-----REKQHQRGLSASYLEPDRYDEEEEGE----ESVSLAAIKNRYKGGIREE 613

  Fly   626 ------EDTEDHMDDDASW-----SSPNSQEEGKQS---SSEDDLPIGGAIRKPTRLVYSGSDSD 676
                  .|:::..::|.:.     ...||.|||:.|   .:|||   ..|.:|..:.|.|..:.:
  Rat   614 RARIYSSDSDEGSEEDKAQRLLKAKKLNSDEEGESSGKRKAEDD---DKANKKHKKYVISDEEEE 675

  Fly   677  676
              Rat   676  675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10887	NP_650866.1	Leo1	396..559	CDD:461126	59/167 (35%)
Leo1	NP_001005548.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..373		80/395 (20%)
		MSCRAMM_ClfA	<11..373	CDD:468110	78/392 (20%)
		Leo1	386..548	CDD:461126	58/164 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	559..596		9/45 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	613..678		16/66 (24%)