Protein Alignment Rh3 and OPN1SW

DIOPT Version :10

• Sequence 1: NP_524411.1
• Gene: Rh3 / 42398
• FlyBaseID: FBgn0003249
• Length: 383
• Species: Drosophila melanogaster
• Sequence 2: NP_001372054.1
• Gene: OPN1SW / 611
• HGNCID: 1012
• Length: 345
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 89/387 - (22%)
• Similarity: 169/387 - (43%)
• Gaps: 74/387 - (19%)

  Fly    10 LFGNVSTALRPEARLSAETRLLG-WNVPPEELRHIPEHWLTYPEPPESMNYLLGTLYIF-FTLMS 72
            ||.|:|:              :| |:.|.   .||...|..|.:..     .:||:::. |.|
Human     8 LFKNISS--------------VGPWDGPQ---YHIAPVWAFYLQAA-----FMGTVFLIGFPL-- 48

  Fly    73 MLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVKT--PIFIYNSFHQGY-ALGHLGCQIFG 134
               |.:|:......|.||.|.|.:::|::|..|::.:.:  |:|:.:.  .|| ..|...|.:.|
Human    49 ---NAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASC--NGYFVFGRHVCALEG 108

  Fly   135 IIGSYTGIAAGATNAFIAYDRFNVITRPMEGKMTHGKAIAMIIFIYMYATPWVVACYTET----- 194
            .:|:..|:..|.:.||:|::|:.||.:|. |........|:.:.:   || |.:......
Human   109 FLGTVAGLVTGWSLAFLAFERYIVICKPF-GNFRFSSKHALTVVL---AT-WTIGIGVSIPPFFG 168

  Fly   195 WGRFVPEGYLTSCTFDYLT--DNFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRD 257
            |.||:|||...||..|:.|  ..:.:..:...:|.|.|:.|.::|.:.|:|::       :||:.
Human   169 WSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLL-------RALKA 226

  Fly   258 QAKKMNVESLRSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFG-----DKTLLTP 317
            .|.:.. ||..:      :.||..:::..:.:...|...:.||...::.....     |..|:|
Human   227 VAAQQQ-ESATT------QKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVT- 283

  Fly   318 GATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLALNEKAPESSA----VASTSTTQ 375
                ||:...|.....:|.:|...:.:::..:.|.....|:.:::...|:    |::.|:||
Human   284 ----IPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSSTQ 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh3	NP_524411.1	7tmA_photoreceptors_insect	59..349	CDD:320207	71/305 (23%)
		TM helix 1	60..86	CDD:320207	6/26 (23%)
		TM helix 2	93..118	CDD:320207	6/26 (23%)
		TM helix 3	130..160	CDD:320207	10/29 (34%)
		TM helix 4	170..190	CDD:320207	4/19 (21%)
		TM helix 5	218..247	CDD:320207	7/28 (25%)
		TM helix 6	277..307	CDD:320207	5/29 (17%)
		TM helix 7	317..342	CDD:320207	5/24 (21%)
OPN1SW	NP_001372054.1	7tmA_SWS1_opsin	32..311	CDD:320204	72/314 (23%)
		TM helix 1	33..59	CDD:320204	6/35 (17%)
		TM helix 2	66..93	CDD:320204	6/26 (23%)
		TM helix 3	104..134	CDD:320204	10/29 (34%)
		TM helix 4	145..167	CDD:320204	4/25 (16%)
		TM helix 5	194..224	CDD:320204	7/36 (19%)
		TM helix 6	239..269	CDD:320204	5/29 (17%)
		TM helix 7	279..304	CDD:320204	7/29 (24%)