Protein Alignment Rh3 and rho

DIOPT Version :10

• Sequence 1: NP_524411.1
• Gene: Rh3 / 42398
• FlyBaseID: FBgn0003249
• Length: 383
• Species: Drosophila melanogaster
• Sequence 2: NP_571159.2
• Gene: rho / 30295
• ZFINID: ZDB-GENE-990415-271
• Length: 354
• Species: Danio rerio
• Alignment Length: 352
• Identity: 94/352 - (26%)
• Similarity: 143/352 - (40%)
• Gaps: 56/352 - (15%)

  Fly    44 PEHWLTYPEPPESMNYLLGTLYIFFTLMSMLG-NGLVIWVFSAAKSLRTPSNILVINLAFCD-FM 106
            |:::|..|     ..|.|...|:||.:::... |.|.::|....|.||||.|.:::|||..| ||
Zfish    27 PQYYLVAP-----WAYGLLAAYMFFLIITGFPVNFLTLYVTIEHKKLRTPLNYILLNLAIADLFM 86

  Fly   107 MMVKTPIFIYNSFHQGYALGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG-KMTHG 170
            :.......:|.|.|..:..|.|||.:.|...:..|.....:...:|.:|:.|:.:|:.. :....
Zfish    87 VFGGFTTTMYTSLHGYFVFGRLGCNLEGFFATLGGEMGLWSLVVLAIERWMVVCKPVSNFRFGEN 151

  Fly   171 KAIAMIIFIYMYATPWVVACYTET-----WGRFVPEGYLTSCTFDYL--TDNFDTRLFVACIFFF 228
            .||..:.|      .||:||....     |.|::|||...||..||.  |...:...||..:|..
Zfish   152 HAIMGVAF------TWVMACSCAVPPLVGWSRYIPEGMQCSCGVDYYTRTPGVNNESFVIYMFIV 210

  Fly   229 SFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLRSNVDKNKETAEIRIAKAAITICFLF 293
            .|..|..:|.:.|.::|..|  .|.|.:.|      ||      :..:.||..:.:..|.:...|
Zfish   211 HFFIPLIVIFFCYGRLVCTV--KEAAAQQQ------ES------ETTQRAEREVTRMVIIMVIAF 261

  Fly   294 FCSWTPY-GVMSLI-----GAFGDKTLLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKR 352
            ...|.|| ||...|     ..||      |....:||...|..|..:|.:|...:.::|     .
Zfish   262 LICWLPYAGVAWYIFTHQGSEFG------PVFMTLPAFFAKTSAVYNPCIYICMNKQFR-----H 315

  Fly   353 CPWLAL----NEKAPESSAVASTSTTQ 375
            |....|    |....|..|..:.|.|:
Zfish   316 CMITTLCCGKNPFEEEEGASTTASKTE 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh3	NP_524411.1	7tmA_photoreceptors_insect	59..349	CDD:320207	84/305 (28%)
		TM helix 1	60..86	CDD:320207	7/26 (27%)
		TM helix 2	93..118	CDD:320207	8/25 (32%)
		TM helix 3	130..160	CDD:320207	6/29 (21%)
		TM helix 4	170..190	CDD:320207	5/19 (26%)
		TM helix 5	218..247	CDD:320207	8/28 (29%)
		TM helix 6	277..307	CDD:320207	10/35 (29%)
		TM helix 7	317..342	CDD:320207	7/24 (29%)
rho	NP_571159.2	Rhodopsin_N	3..37	CDD:313611	3/14 (21%)
		7tmA_MWS_opsin	38..317	CDD:381742	83/309 (27%)
		TM helix 1	39..65	CDD:381742	7/25 (28%)
		TM helix 2	72..99	CDD:381742	8/26 (31%)
		TM helix 3	110..140	CDD:381742	6/29 (21%)
		'Ionic lock' involved in activated form stabilization. /evidence=ECO:0000250|UniProtKB:P02699	134..136		0/1 (0%)
		TM helix 4	151..173	CDD:381742	7/27 (26%)
		TM helix 5	200..230	CDD:381742	8/29 (28%)
		TM helix 6	245..275	CDD:381742	9/29 (31%)
		TM helix 7	285..310	CDD:381742	7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..354		3/10 (30%)