Protein Alignment Rh3 and Opn3

DIOPT Version :10

• Sequence 1: NP_524411.1
• Gene: Rh3 / 42398
• FlyBaseID: FBgn0003249
• Length: 383
• Species: Drosophila melanogaster
• Sequence 2: NP_034228.1
• Gene: Opn3 / 13603
• MGIID: 1338022
• Length: 400
• Species: Mus musculus
• Alignment Length: 329
• Identity: 83/329 - (25%)
• Similarity: 142/329 - (43%)
• Gaps: 37/329 - (11%)

  Fly    51 PEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVKTPIFI 115
            |...|.:..|||.|    .|:.:.||.||:.::|....||||:::.::||:..|.::.:....|.
Mouse    36 PTAYERLALLLGCL----ALLGVGGNLLVLLLYSKFPRLRTPTHLFLVNLSLGDLLVSLFGVTFT 96

  Fly   116 YNS-FHQGYALGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEGKMTHGKAI------ 173
            :.| ...|:....:||...|..||..|..:..|...:||:|:.        ::.|.:.|
Mouse    97 FASCLRNGWVWDAVGCAWDGFSGSLFGFVSITTLTVLAYERYI--------RVVHARVINFSWAW 153

  Fly   174 AMIIFIYMYATPWVVACYTETWGRFVPEGYLTSCTFDYLTDNFDTRLFVACIFFFSFVCPTTMIT 238
            ..|.:|::|:..|..|... .|.|::.:.:...||.|:.:.:.:...||..:|....|.|..:|.
Mouse   154 RAITYIWLYSLAWAGAPLL-GWNRYILDIHGLGCTVDWRSKDANDSSFVLFLFLGCLVVPVGIIA 217

  Fly   239 YYYSQIVGHVFSHEKALRDQAKKMNVESLRSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVM 303
            :.|    ||:....:.||      .||.|::.........|.::||....:.|:|...|.||.|.
Mouse   218 HCY----GHILYSVRMLR------CVEDLQTIQVIKMLRYEKKVAKMCFLMAFVFLTCWMPYIVT 272

  Fly   304 SLIGAFGDKTLLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQK-------RCPWLALNEK 361
            ..:...|...|:||..:::.....|.....:|.:|...:.::|..|.:       ||...|.|..
Mouse   273 RFLVVNGYGHLVTPTVSIVSYLFAKSSTVYNPVIYIFMNRKFRRSLLQLLCFRLLRCQRPAKNLP 337

  Fly   362 APES 365
            |.||
Mouse   338 AAES 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh3	NP_524411.1	7tmA_photoreceptors_insect	59..349	CDD:320207	73/296 (25%)
		TM helix 1	60..86	CDD:320207	10/25 (40%)
		TM helix 2	93..118	CDD:320207	4/24 (17%)
		TM helix 3	130..160	CDD:320207	9/29 (31%)
		TM helix 4	170..190	CDD:320207	5/25 (20%)
		TM helix 5	218..247	CDD:320207	7/28 (25%)
		TM helix 6	277..307	CDD:320207	9/29 (31%)
		TM helix 7	317..342	CDD:320207	4/24 (17%)
Opn3	NP_034228.1	7tm_GPCRs	64..317	CDD:475119	64/271 (24%)
		TM helix 2	75..97	CDD:410628	4/21 (19%)
		TM helix 3	113..135	CDD:410628	5/21 (24%)
		TM helix 4	154..170	CDD:410628	4/15 (27%)
		TM helix 5	198..221	CDD:410628	7/26 (27%)
		TM helix 6	252..274	CDD:410628	8/21 (38%)
		TM helix 7	286..311	CDD:410628	4/24 (17%)