Protein Alignment mdlc and CWC24

DIOPT Version :9

• Sequence 1: NP_650865.1
• Gene: mdlc / 42397
• FlyBaseID: FBgn0038772
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_013427.1
• Gene: CWC24 / 851033
• SGDID: S000004315
• Length: 259
• Species: Saccharomyces cerevisiae
• Alignment Length: 329
• Identity: 99/329 - (30%)
• Similarity: 151/329 - (45%)
• Gaps: 106/329 - (32%)

  Fly    13 FKKRNLKKGAGIRRKKETSSDESAKSSDEETKGKASALVRAENRRKRTNPNFQSTKTMSKAKRQA 77
            |:||.:.|         :||||                   :|::||...||...|.:
Yeast     2 FRKRLVNK---------SSSDE-------------------KNQKKRQKINFSEEKLV------- 31

  Fly    78 GGVGDDGSSSASDDDKLGIAYKSKREALPSGPQDQGATSINEMDTELDRDAQAIHARALKINEEL 142
                      |||::|                   |::.:..:       |::.::|.|:::.|.
Yeast    32 ----------ASDEEK-------------------GSSDLMSL-------AKSGNSRTLQLSHEN 60

  Fly   143 EGKA---------------DDKIYRGINNY-----AQYYKKQDTAAGNA----SSGMVR--SGPI 181
            |||.               ||.....:.|:     |:..||:..:..|.    .||..:  :..|
Yeast    61 EGKLQKKGEDLDKYTLTVNDDSTKEDLLNFERKELAEKAKKRRPSDDNELVLNMSGKNKRLTKQI 125

  Fly   182 RAPAHLRATVRWDYQPDICKDYKETGYCGFGDSCKFLHDRSDYKAGWQLEMDHENQRTGDVDSDG 246
            ..|.::|.||..|:|||:|||||:|||||:||||||||.|.|:|.||:|     ||   :.::|.
Yeast   126 NQPTNIRTTVLMDFQPDVCKDYKQTGYCGYGDSCKFLHSRDDFKTGWKL-----NQ---EWNADK 182

  Fly   247 DDTKYEIHSDEETLPFKCHICRQSFVNPVVTKCKHYFCEKCALAQYKKSQRCIICSQQTNGIFNP 311
            :|:| .:..|.|.:||||.:|::.:.:||||.|.||||..|.....||..:|.||.::|:|....
Yeast   183 EDSK-AVTLDLEKIPFKCTLCKEDYKSPVVTNCGHYFCGSCFAKDMKKGTKCFICHKETHGSAKV 246

  Fly   312 AKEL 315
            |.:|
Yeast   247 ASDL 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mdlc	NP_650865.1	COG5152	<181..320	CDD:227481	64/135 (47%)
		zf-CCCH	195..221	CDD:279036	21/25 (84%)
		zf-RING_5	263..303	CDD:291308	18/39 (46%)
CWC24	NP_013427.1	COG5152	1..259	CDD:227481	99/329 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344722
Domainoid	1	1.000	56	1.000	Domainoid score	I2712
eggNOG	1	0.900	-	-		E1_COG5152
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1150
Isobase	1	0.950	-	0	Normalized mean entropy	S1119
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003160
OrthoInspector	1	1.000	-	-		oto99318
orthoMCL	1	0.900	-	-		OOG6_102529
Panther	1	1.100	-	-	LDO	PTHR12930
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2079
SonicParanoid	1	1.000	-	-		X2126
TreeFam	1	0.960	-	-
	13	12.730