Protein Alignment mdlc and Rnf113a2

DIOPT Version :9

• Sequence 1: NP_650865.1
• Gene: mdlc / 42397
• FlyBaseID: FBgn0038772
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_079801.2
• Gene: Rnf113a2 / 66381
• MGIID: 1913631
• Length: 337
• Species: Mus musculus
• Alignment Length: 369
• Identity: 196/369 - (53%)
• Similarity: 238/369 - (64%)
• Gaps: 46/369 - (12%)

  Fly     1 MSEEAASTSS------FGFKKRNLKKGAGIRRKK---ETSSDESAKSSDEETKGKASALVRAENR 56
            |:|:.:...|      |.|||...|..|| |||:   :..|.||..||||     ..::||.|.:
Mouse     1 MAEQVSQGKSEDQVCTFLFKKPGRKGSAG-RRKRPACDPESGESGSSSDE-----GCSVVRPEKK 59

  Fly    57 RKRTNPNFQSTKTMSKAKRQAGGVGDDGSSSASD---DDKLGIAYKSKREALPSGPQDQGATSIN 118
            |...||..|.|....|.|    |...|.||...:   ::.||:.|||.|.|.|.||:|.|||::.
Mouse    60 RAAHNPMIQKTSGSGKQK----GAYCDLSSEEEEKAGNESLGVVYKSTRSAKPVGPEDMGATAVY 120

  Fly   119 EMDTELDRDAQAIHARALKINEELEGKADDKIYRGINNYAQYYKKQDTAAGNASSGMVRSGPIRA 183
            |:|||.:||||||..|:.||.|||.||.|||||||||||.:|.|.:||:.|||||||||.|||||
Mouse   121 ELDTEKERDAQAIFERSQKIQEELRGKEDDKIYRGINNYQKYMKPKDTSMGNASSGMVRKGPIRA 185

  Fly   184 PAHLRATVRWDYQPDICKDYKETGYCGFGDSCKFLHDRSDYKAGWQLEMDHENQRTGDVDSDGDD 248
            |.||||||||||||||||||||||:|||||||||||||||||.|||:|.:.:..|.|..    :|
Mouse   186 PEHLRATVRWDYQPDICKDYKETGFCGFGDSCKFLHDRSDYKHGWQIERELDEGRYGVY----ED 246

  Fly   249 TKYEIHSDEETLPFKCHICRQSFVNPVVTKCKHYFCEKCALAQYKKSQRCIICSQQTNGIFNPAK 313
            ..||:.||:|.:||||.||||:|.|||||||||||||.|||..::.:.||.:|.|||:|:|||||
Mouse   247 ENYEVESDDEEIPFKCFICRQTFQNPVVTKCKHYFCETCALQHFRTTPRCYVCEQQTHGVFNPAK 311

  Fly   314 ELIARLKTNPMENSDSDEEEEFGKKEDKAEAGEEAQEISSDDSD 357
            ||||:|                 :|..|||.|..:   :.:|:|
Mouse   312 ELIAKL-----------------EKYRKAEGGASS---TPEDAD 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mdlc	NP_650865.1	COG5152	<181..320	CDD:227481	96/138 (70%)
		zf-CCCH	195..221	CDD:279036	24/25 (96%)
		zf-RING_5	263..303	CDD:291308	26/39 (67%)
Rnf113a2	NP_079801.2	COG5152	57..323	CDD:227481	168/290 (58%)
		zf-CCCH	197..223	CDD:279036	24/25 (96%)
		RING	261..299	CDD:238093	25/37 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842100
Domainoid	1	1.000	183	1.000	Domainoid score	I3428
eggNOG	1	0.900	-	-		E1_COG5152
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2076
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55322
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003160
OrthoInspector	1	1.000	-	-		otm42940
orthoMCL	1	0.900	-	-		OOG6_102529
Panther	1	1.100	-	-	O	PTHR12930
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2126
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.800