Protein Alignment mdlc and rnf-113

DIOPT Version :9

• Sequence 1: NP_650865.1
• Gene: mdlc / 42397
• FlyBaseID: FBgn0038772
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_499375.1
• Gene: rnf-113 / 176507
• WormBaseID: WBGene00010476
• Length: 384
• Species: Caenorhabditis elegans
• Alignment Length: 350
• Identity: 159/350 - (45%)
• Similarity: 205/350 - (58%)
• Gaps: 43/350 - (12%)

  Fly    14 KKRNLKKGAGIRRKKETSSDESAKSSDEETKGKASALVRAENRRKRTNPNFQSTKTMSKAKRQAG 78
            ||||    |.:.||||:||||   ..|.|.|.       ...:|:||||..||||.:..:.|:|.
 Worm     8 KKRN----APVVRKKESSSDE---DQDSEVKD-------VIQKRRRTNPMVQSTKQLDASTRRAD 58

  Fly    79 GVGDDGSSSASDDDKLGIA---YKSKREALPSGPQDQGATSINEMDTELDRDAQAIHARA---LK 137
            ...|| |..:.|:..:.:|   :.:..:|.||||:|||||:..|:||:...||||...|.   ||
 Worm    59 NSSDD-SDDSDDNQDIAVATHSFAASGDAGPSGPRDQGATATLEVDTDYSHDAQAQFERVQQQLK 122

  Fly   138 INEELEGKADDKIYRGINNYAQYYKKQDTAAGNASSGMVRSGPIRAPAHLRATVRWDYQPDICKD 202
            ...|.:||.   :|:|...|.....| |||.|||:||..|.||:|||..||.|||||:.||||||
 Worm   123 EGVEKDGKI---LYKGSALYGAKEAK-DTAKGNAASGYNRVGPVRAPQFLRQTVRWDFAPDICKD 183

  Fly   203 YKETGYCGFGDSCKFLHDRSDYKAGWQLEMDHENQRTGDVDSDGDDTKYEIHSDEETLPFKCHIC 267
            |||||:|.|||||||:|||||||.||:::.::|..:.|    ..||..||||..::|.|..|.||
 Worm   184 YKETGFCTFGDSCKFVHDRSDYKHGWEIDEEYEAGKYG----AEDDANYEIHEGDDTFPEDCFIC 244

  Fly   268 RQSFVNPVVTKCKHYFCEKCALAQYKKSQRCIICSQQTNGIFNPAKELIARLKTNPMENSDSDEE 332
            ...||:|:|||||||||..|||..::||.:|.||.|.|..|.|.||||:..||..
 Worm   245 GNPFVDPIVTKCKHYFCTGCALKSFQKSSKCPICQQNTENIMNTAKELLTYLKRK---------- 299

  Fly   333 EEFGKKEDKAEAGEEAQEISSDDSD 357
                |::.|.||.::.:|..|||.:
 Worm   300 ----KQQQKQEAEKQEEEKDSDDDE 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mdlc	NP_650865.1	COG5152	<181..320	CDD:227481	79/138 (57%)
		zf-CCCH	195..221	CDD:279036	20/25 (80%)
		zf-RING_5	263..303	CDD:291308	23/39 (59%)
rnf-113	NP_499375.1	zf-CCCH	180..202	CDD:279036	18/21 (86%)
		RING	240..282	CDD:238093	24/41 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162246
Domainoid	1	1.000	113	1.000	Domainoid score	I3863
eggNOG	1	0.900	-	-		E1_COG5152
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H133822
Inparanoid	1	1.050	280	1.000	Inparanoid score	I1762
Isobase	1	0.950	-	0	Normalized mean entropy	S1119
OMA	1	1.010	-	-		QHG55322
OrthoDB	1	1.010	-	-		D1420266at2759
OrthoFinder	1	1.000	-	-		FOG0003160
OrthoInspector	1	1.000	-	-		oto20646
orthoMCL	1	0.900	-	-		OOG6_102529
Panther	1	1.100	-	-	LDO	PTHR12930
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2079
SonicParanoid	1	1.000	-	-		X2126
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750