Protein Alignment Regnase-1 and zc3h12a

DIOPT Version :9

• Sequence 1: NP_650863.3
• Gene: Regnase-1 / 42394
• FlyBaseID: FBgn0038769
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_021322483.1
• Gene: zc3h12a / 798235
• -ID: -
• Length: 579
• Species: Danio rerio
• Alignment Length: 596
• Identity: 202/596 - (33%)
• Similarity: 286/596 - (47%)
• Gaps: 163/596 - (27%)

  Fly    58 RQNLEFAKKLGYSEQSIHSALTRLGSEAKQNELLAELIKLTADAPRP------------AHIGGG 110
            :..::|.:|||||.|.:.:||.:||.....|.:|.||::..|.|..|            :| .||
Zfish    23 QMKVDFFRKLGYSPQEVKAALRKLGLGTDTNAVLGELVRSGAKAVPPSVSNSDDGGSGSSH-RGG 86

  Fly   111 GSPSSMTSTLSSPTGGSNSSGLRHIVIDGSNVALSHGNNLVFSCRGIRICVDWFRQRGHRDITAF 175
            ||.....|||...|  ...|.|:.|||||||||:||||..|||||||.:.|::|..||||:||.|
Zfish    87 GSSRGQGSTLDDAT--EAESDLKPIVIDGSNVAMSHGNKEVFSCRGIELAVNYFLDRGHRNITVF 149

  Fly   176 VPNWRKEMANNN--IADQELLYELEHERYLVFTPSRHLDGKRVSCYDDRFILKLAVETDGIVVSN 238
            ||:||||....:  |:||.:|.|||.:::|||||||.:.||||.|||||||:|||.:.|||:|||
Zfish   150 VPSWRKEQPRPDVPISDQHILGELERKKFLVFTPSRRVGGKRVVCYDDRFIVKLAHDLDGIIVSN 214

  Fly   239 DNYRDLILESNEFRRVVQERLLMYSFVNDIFMPPDDPLGRSGPNLDLFLCSQTQQKMAD-AQQLC 302
            |.||||..|..|::|.::|||||||||||.||||||||||.|||||.||  :.:..:.| .:|||
Zfish   215 DTYRDLQSERPEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPNLDNFL--RKKAMLIDHKRQLC 277

  Fly   303 PYGKKCTYGQKCKFRHHNQAPLLQRLPLQASHSAPLHTNGGQQLVSPGGNNNNVKINSLISREPL 367
            |||||||||.||||.|                  |..||..|:.::     :.::.|:.:|
Zfish   278 PYGKKCTYGIKCKFYH------------------PERTNQSQRSLA-----DELRENARLS---- 315

  Fly   368 GRTKSNTIEQVCQGFSAQMDLSEGAVESSQPNRHKKLQRQ---QPPPA-------------YRLL 416
            |..:...:....:|...:.|..     |..|:..::|:::   :|..:             ..:.
Zfish   316 GSKEDCRVSGSLRGVYPRNDPG-----SCSPSLEQELEKKLSLEPESSDSRDVLLHYWDDIMSMK 375

  Fly   417 VPTYSAPLQQQQHQAQQQHQQSNSSTNYHHQYLTRTPSAPVTDQGLGL----------------- 464
            .|..:||:        .|:......|:.|..| ::.||...:|.|||.
Zfish   376 KPLNTAPV--------GQYSALGDRTSLHAPY-SKNPSIFSSDSGLGSYESQFSEQSQSFDELHR 431

  Fly   465 ------PLPA-----------HNFAHLSA------------------------------------ 476
                  |:|.           :|.:|.|:
Zfish   432 IRSGHPPMPGNPAVPAGGHYYNNISHFSSLQPNYTAYSSLPLPNPVQSYSLPACGGWSYPYYLTQ 496

  Fly   477 ---------SDSRINEELHASQQLPR-------EEQRRLLRYHLGSLFPPHQVHAVLQLYPEETD 525
                     |.|..:..::.|||...       :|:|..:|..|.::|.|..|:.|:.::|:..|
Zfish   497 ATGLAEPLTSRSSQSAGVYGSQQHSAMTQSNAFQEEREEVRKKLYAIFNPRHVNKVMDMFPQLKD 561

  Fly   526 AKTICAAILNL 536
            |:.:.|.:|.|
Zfish   562 AQQLAAEVLKL 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Regnase-1	NP_650863.3	RNase_Zc3h12a	131..284	CDD:288804	102/154 (66%)
zc3h12a	XP_021322483.1	RNase_Zc3h12a	105..261	CDD:314796	103/155 (66%)
		zf-CCCH	273..295	CDD:279036	17/39 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D335949at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010